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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Myocd
myocardin
MGI:2137495
36 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Myocdem1Blk/Myocdtm1.1Msp
involves: 129 		abnormal urinary bladder detrusor smooth muscle morphology J:283803
abnormal urinary bladder morphology J:283803
normal cardiovascular system phenotype J:283803
distended urinary bladder J:283803
postnatal lethality, complete penetrance J:283803
Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
involves: 129 * C57BL/6 		cardiac edema J:217513
embryonic growth retardation J:217513
embryonic lethality, complete penetrance J:217513
Myocdtm1(cre)Jomm/Myocd+
Not Specified 		no abnormal phenotype detected J:149882
Myocdtm1.1Msp/Myocdtm1.1Msp
involves: 129/Sv * C57BL/6 		embryonic lethality during organogenesis, complete penetrance J:131288
Myocdtm1Eno/Myocdtm1Eno
involves: 129S/SvEv * C57BL/6 		abnormal blood vessel morphology J:84789
abnormal dorsal aorta morphology J:84789
abnormal vascular smooth muscle morphology J:84789
absent vitelline blood vessels J:84789
normal cardiovascular system phenotype J:84789
embryonic growth retardation J:84789
embryonic lethality during organogenesis, complete penetrance J:84789
pale yolk sac J:84789
pericardial effusion J:84789
Myocdtm1Msp/Myocdtm1Msp
involves: 129 		abnormal myocardial fiber morphology J:154666
increased cardiomyocyte apoptosis J:154666
Myocdtm1Msp/Myocdtm1Msp
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: 129/Sv * C57BL/6J * FVB/N 		abnormal intercalated disk morphology J:154666
abnormal myocardial fiber morphology J:154666
abnormal sarcomere morphology J:154666
cardiac fibrosis J:154666
decreased cardiac muscle contractility J:154666
dilated cardiomyopathy J:154666
enlarged heart J:154666
increased cardiomyocyte apoptosis J:154666
myocardial fiber degeneration J:154666
myocardial fiber disarray J:154666
pericardial effusion J:154666
premature death J:154666
Myocdtm1Msp/Myocdtm1Msp
H2az2Tg(Wnt1-cre)11Rth/H2az2+
involves: 129/Sv * C57BL/6 * CBA 		abnormal angiogenesis J:131288
abnormal vascular smooth muscle morphology J:131288
cyanosis J:131288
patent ductus arteriosus J:131288
postnatal lethality, complete penetrance J:131288
Myocdtm1Msp/Myocdtm1Msp
Tg(Myh6-cre)2182Mds/0
involves: 129/Sv * FVB/N 		abnormal atrial thrombosis J:154666
abnormal cardiac thrombosis J:154666
abnormal heart echocardiography feature J:154666
abnormal intercalated disk morphology J:154666
abnormal myocardial fiber morphology J:154666
abnormal sarcomere morphology J:154666
cardiac fibrosis J:154666
decreased cardiac muscle contractility J:154666
dilated cardiomyopathy J:154666
enlarged heart J:154666
increased heart atrium size J:154666
increased heart ventricle size J:154666
myocardial fiber degeneration J:154666
pericardial effusion J:154666
postnatal lethality, incomplete penetrance J:154666
premature death J:154666
Myocdtm1Msp/Myocdtm1Msp
Tg(Pax3-cre)1Joe/0
involves: 129/Sv * C57BL/6 * SJL 		patent ductus arteriosus J:131288
postnatal lethality, complete penetrance J:131288
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory