Twsg1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Twsg1
twisted gastrulation BMP signaling modulator 1
MGI:2137520

31 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmp4^tm1Blh/Bmp4⁺ Twsg1^tm1Emdr/Twsg1^tm1Emdr involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * SJL	abnormal caudal vertebrae morphology	J:90398
	abnormal craniofacial morphology	J:90398
	abnormal diencephalon morphology	J:90398
	abnormal forebrain morphology	J:90398
	abnormal lateral ganglionic eminence morphology	J:90398
	abnormal lens induction	J:90398
	abnormal mouth morphology	J:90398
	abnormal nose morphology	J:90398
	abnormal retina morphology	J:90398
	abnormal tail morphology	J:90398
	absent mandible	J:90398
	absent nasal septum	J:90398
	absent tongue	J:90398
	anophthalmia	J:90398
	holoprosencephaly	J:90398
	kinked tail	J:90398
	lowered ear position	J:90398
	oral atresia	J:90398
	short tail	J:90398
	single external naris	J:90398
Bmp4^tm2Blh/Bmp4⁺ Twsg1^tm1.1Mboc/Twsg1^tm1.1Mboc involves: 129S/SvEv * C57BL/6 * FVB/N	normal craniofacial phenotype	J:88784
Bmper^tm1Emdr/Bmper⁺ Twsg1^tm1Emdr/Twsg1^tm1Emdr involves: 129 * C57BL/6 * SJL	prenatal lethality, incomplete penetrance	J:141243
Bmper^tm1Emdr/Bmper^tm1Emdr Twsg1^tm1Emdr/Twsg1^tm1Emdr involves: 129 * C57BL/6 * SJL	abnormal vertebral column morphology	J:141243
	normal mortality/aging	J:141243
	normal skeleton phenotype	J:141243
Chrd^tm1Emdr/Chrd^tm1Emdr Twsg1^tm1.1Mboc/Twsg1^tm1.1Mboc involves: 129/Sv * C57BL/6 * FVB/N	abnormal mandible morphology	J:88784
	abnormal vertebral arch morphology	J:88784
	normal nervous system phenotype	J:88784
	perinatal lethality	J:88784
Trp53^tm1Brd/Trp53^tm1Brd Twsg1^tm1.1Mboc/Twsg1^tm1.1Mboc involves: 129S7/SvEvBrd * C57BL/6	abnormal craniofacial morphology	J:173627
	exencephaly	J:173627
	perinatal lethality, incomplete penetrance	J:173627

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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