Dtnbp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dtnbp1
dystrobrevin binding protein 1
MGI:2137586

42 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dtnbp1^sdy-Btlr/Dtnbp1^sdy-Btlr C57BL/6J-Dtnbp1^sdy-Btlr	diluted coat color	J:133620
	impaired natural killer cell mediated cytotoxicity	J:133620
	increased susceptibility to Herpesvirales infection	J:133620
Dtnbp1^sdy/Dtnbp1⁺ DBA/2J-Dtnbp1^sdy/J	hypoalgesia	J:143912
Dtnbp1^sdy/Dtnbp1⁺ DBA/2J-Dtnbp1^sdy/J	impaired short-term object recognition memory	J:143912
Dtnbp1^sdy/Dtnbp1^sdy B6J.D2-Dtnbp1^sdy	abnormal circadian behavior	J:223954
	abnormal operant conditioning behavior	J:197066
	decreased anxiety-related response	J:223954
	decreased prepulse inhibition	J:223954
	normal homeostasis/metabolism phenotype	J:223954
	increased locomotor activity	J:223954
Dtnbp1^sdy/Dtnbp1^sdy DBA/2J-Dtnbp1^sdy/J	abnormal behavioral response to amphetamine	J:143912
	abnormal habituation to a new environment	J:143912
	decreased eye pigmentation	J:14267
	diluted coat color	J:14267
	enhanced cued conditioning behavior	J:143912
	hypoalgesia	J:143912
	impaired short-term object recognition memory	J:143912
	increased bleeding time	J:14267
Dtnbp1^sdy/Dtnbp1^sdy involves: DBA/2J	abnormal choroid melanin granule morphology	J:85123
	abnormal eye pigmentation	J:1958
	abnormal kidney physiology	J:1958
	abnormal optic choroid morphology	J:85123
	abnormal platelet physiology	J:85123, J:323340
	abnormal retina pigment epithelium morphology	J:85123
	normal behavior/neurological phenotype	J:85123
	decreased platelet aggregation	J:85123
	decreased platelet dense granule number	J:1958, J:85123
	decreased platelet serotonin level	J:85123
	diluted coat color	J:1958
	increased bleeding time	J:1958
	normal muscle phenotype	J:85123
	thrombocytopenia	J:1958
Dtnbp1^{tm1b(EUCOMM)Hmgu}/Dtnbp1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Dtnbp1^{tm1b(EUCOMM)Hmgu}/Tcp	abnormal coat/hair pigmentation	J:211773
	abnormal iris pigmentation	J:211773
	abnormal retina morphology	J:211773
	abnormal uterus morphology	J:211773
	decreased exploration in new environment	J:211773
	decreased grip strength	J:211773
	decreased lymphocyte cell number	J:211773
	increased circulating glucose level	J:211773
	increased circulating phosphate level	J:211773
	increased fasting circulating glucose level	J:211773
	increased leukocyte cell number	J:211773
	increased lymphocyte cell number	J:211773
	increased neutrophil cell number	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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