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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Trp53bp2
transformation related protein 53 binding protein 2
MGI:2138319
5 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Trp53tm1Brd/Trp53+
Trp53bp2tm1Cdlo/Trp53bp2+
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
increased tumor incidence J:146764
Trp53tm1Tyj/Trp53+
Trp53bp2tm1Xlu/Trp53bp2+
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
increased lymphoma incidence J:108701
increased tumor incidence J:108701
Trp53tm1Tyj/Trp53+
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
prenatal lethality, incomplete penetrance J:108701
Trp53tm1Tyj/Trp53tm1Tyj
Trp53bp2tm1Xlu/Trp53bp2tm1Xlu
involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
embryonic lethality during organogenesis, complete penetrance J:108701
Trp53bp2tm1Cdlo/Trp53bp2+
Tg(EmuSR-tTa)83Bop/0
Tg(tetO-MYC)36aBop/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
increased T cell derived lymphoma incidence J:146764

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory