Dlgap4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dlgap4
DLG associated protein 4
MGI:2138865

27 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dlgap4^Gt(XH723)Byg/Dlgap4^Gt(XH723)Byg B6.129P2-Dlgap4^Gt(XH723)Byg	abnormal excitatory postsynaptic currents	J:277713
	abnormal habituation to a new environment	J:277713
	abnormal learning/memory/conditioning	J:277713
	abnormal miniature excitatory postsynaptic currents	J:277713
	abnormal motor coordination/balance	J:277713
	abnormal nervous system electrophysiology	J:277713
	abnormal posture	J:277713
	abnormal response to social novelty	J:277713
	abnormal social/conspecific interaction behavior	J:277713
	abnormal spatial working memory	J:277713
	decreased anxiety-related response	J:277713
	decreased exploration in new environment	J:277713
	decreased grooming behavior	J:277713
	decreased vocalization	J:277713
	impaired spatial learning	J:277713
	increased locomotor activity	J:277713
	reduced long-term depression	J:277713
	social withdrawal	J:277713
Dlgap4^Gt(XH723)Byg/Dlgap4^Gt(XH723)Byg Tg(Thy1-EGFP)MJrs/0 involves: 129P2/OlaHsd * C57BL/6J * CBA	abnormal dendritic stubby spine morphology	J:277713
	abnormal hippocampal pyramidal neuron dendrite morphology	J:277713
	abnormal postsynaptic density morphology	J:277713
Dlgap4^{tm1b(KOMP)Wtsi}/Dlgap4⁺ C57BL/6N-Dlgap4^{tm1b(KOMP)Wtsi}/Wtsi	decreased erythrocyte cell number	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased total body fat amount	J:211773
	increased blood urea nitrogen level	J:211773
	increased circulating creatinine level	J:211773
	increased lean body mass	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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