Anapc2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Anapc2
anaphase promoting complex subunit 2
MGI:2139135

13 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Anapc2^tm1Hez/Anapc2^tm1Hez involves: 129 * C57BL/6 * C57BL/6J	no abnormal phenotype detected	J:179044
Anapc2^tm1Kna/Anapc2^tm1Kna Tg(Ttr-cre/Esr1)1Vco/0 involves: 129P2/OlaHsd C57BL/6 * DBA/2	abnormal hepatocyte morphology	J:87782
	increased hepatocyte proliferation	J:87782
	liver failure	J:87782
	premature death	J:87782
Anapc2^tm1Kna/Anapc2^tm2Kna Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal bone marrow morphology	J:87782
	abnormal enzyme/coenzyme level	J:87782
	abnormal hepatocyte morphology	J:87782
	abnormal liver physiology	J:87782
	anemia	J:87782
	decreased hemoglobin content	J:87782
	decreased liver glycogen level	J:87782
	increased circulating bilirubin level	J:87782
	increased hepatocyte proliferation	J:87782
	liver failure	J:87782
	premature death	J:87782
Anapc2^tm2Kna/Anapc2^tm2Kna involves: 129P2/OlaHsd * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:87782

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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