Sall4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sall4
spalt like transcription factor 4
MGI:2139360

68 phenotypes from 13 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sall4^{Gt(RRC044)Byg}/Sall4^{Gt(RRC044)Byg} involves: 129P2/OlaHsd * C57BL/6	embryonic growth arrest	J:138922
	embryonic lethality between implantation and somite formation, complete penetrance	J:138922
Sall4^{Gt(W097E01)Flo}/Sall4^{Gt(W097E01)Flo} involves: 129S2/SvPas * C57BL/6	abnormal developmental patterning	J:138922
	abnormal embryonic epiblast morphology	J:138922
	abnormal gastrulation	J:138922
	abnormal mesendoderm development	J:138922
	abnormal rostral-caudal body axis extension	J:138922
	absent primitive node	J:138922
	decreased embryo size	J:138922
	embryonic growth arrest	J:138922
	embryonic lethality between implantation and somite formation, complete penetrance	J:138922
	small embryonic epiblast	J:138922
Sall4^Gt(XE027)Byg/Sall4⁺ B6;129P2-Sall4^Gt(XE027)Byg	abnormal carpal bone morphology	J:105332
	abnormal digit morphology	J:105332
	abnormal hindlimb bud morphology	J:105332
	abnormal phalanx morphology	J:105332
	elongated metacarpal bones	J:105332
	embryonic lethality during organogenesis, incomplete penetrance	J:105332
Sall4^Gt(XE027)Byg/Sall4⁺ involves: 129P2/OlaHsd * Black Swiss * C57BL/6	abnormal heart development	J:105332
	abnormal interventricular groove morphology	J:105332
	common ventricle	J:105332
	disorganized myocardium	J:105332
	embryonic lethality during organogenesis	J:105332
	muscular ventricular septal defect	J:105332
	thin myocardium	J:105332
Sall4^Gt(XE027)Byg/Sall4^Gt(XE027)Byg B6;129P2-Sall4^Gt(XE027)Byg	embryonic growth arrest	J:138922
	embryonic lethality between implantation and somite formation, complete penetrance	J:105332, J:138922
Sall4^tm1Bili/Sall4⁺ Not Specified	premature death	J:122376
Sall4^tm1Bili/Sall4^tm1Bili Not Specified	prenatal lethality, complete penetrance	J:122376
Sall4^tm1Brd/Sall4⁺ involves: 129S7/SvEvBrd * C57BL/6J	abnormal craniofacial bone morphology	J:117866
	abnormal middle ear morphology	J:117866
	abnormal nasal bone morphology	J:117866
	abnormal perineum morphology	J:117866
	abnormal pinna reflex	J:117866
	absent enteric neurons	J:117866
	absent pinna reflex	J:117866
	absent triquetrum	J:117866
	anal atresia	J:117866
	anovaginal fistula	J:117866
	conductive hearing loss	J:117866
	ear inflammation	J:117866
	exencephaly	J:117866
	impaired hearing	J:117866
	increased susceptibility to otitis media	J:117866
	middle ear effusion	J:117866
	persistent cloaca	J:117866
	postnatal lethality	J:117866
	renal hypoplasia	J:117866
	single kidney	J:117866
Sall4^tm1Brd/Sall4^tm1Brd involves: 129S7/SvEvBrd * C57BL/6J	embryonic lethality between implantation and somite formation, complete penetrance	J:117866
Sall4^tm1Ryn/Sall4⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal anus morphology	J:118119
	abnormal rectum morphology	J:118119
	exencephaly	J:118119
	normal hearing/vestibular/ear phenotype	J:118119
	kinked tail	J:118119
	normal limbs/digits/tail phenotype	J:118119
	megacolon	J:118119
	postnatal lethality, incomplete penetrance	J:118119
	premature death	J:118119
	prenatal lethality, incomplete penetrance	J:118119
	ventricular septal defect	J:118119
	normal vision/eye phenotype	J:118119
Sall4^tm1Ryn/Sall4^tm1Ryn involves: 129P2/OlaHsd * C57BL/6J	abnormal embryonic epiblast morphology	J:118119
	decreased inner cell mass proliferation	J:118119
	embryonic lethality between implantation and somite formation, complete penetrance	J:118119
Sall4^tm1Tre/Sall4⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	absent trophoblast giant cells	J:115635
Sall4^tm1Tre/Sall4^tm1Tre involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	abnormal embryonic tissue morphology	J:115635
	abnormal inner cell mass morphology	J:115635
	embryonic lethality between implantation and somite formation, complete penetrance	J:115635
Sall4^tm1Tre/Sall4^tm2.1Tre involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	embryonic lethality between implantation and somite formation, complete penetrance	J:115635
Sall4^tm1Yam/Sall4⁺ involves: 129S4/SvJae * C57BL/6J	abnormal anal canal morphology	J:158264
	abnormal rectum morphology	J:158264
	exencephaly	J:158264
	lethality throughout fetal growth and development, incomplete penetrance	J:158264
	open neural tube	J:158264
	premature death	J:158264
Sall4^tm1Yam/Sall4^tm1Yam involves: 129S4/SvJae * C57BL/6J	abnormal cell physiology	J:158264
	abnormal primitive endoderm morphology	J:158264
	absent egg cylinders	J:158264
	decreased cell proliferation	J:158264
	decreased inner cell mass proliferation	J:158264
	delayed blastocyst hatching from the zona pellucida	J:158264
	embryonic lethality between implantation and somite formation, complete penetrance	J:158264
Sall4^tm2.1Tre/Sall4^tm2.1Tre involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1	embryonic lethality between implantation and somite formation, complete penetrance	J:115635
Sall4^tm2Ryn/Sall4⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal anus morphology	J:118119
	abnormal rectum morphology	J:118119
	exencephaly	J:118119
	kinked tail	J:118119
	megacolon	J:118119
	postnatal lethality, incomplete penetrance	J:118119
	premature death	J:118119
	prenatal lethality, complete penetrance	J:118119
	ventricular septal defect	J:118119
Sall4^tm2Ryn/Sall4^tm2Ryn involves: 129P2/OlaHsd * C57BL/6J	abnormal embryonic tissue morphology	J:118119
	abnormal inner cell mass morphology	J:118119
	embryonic lethality between implantation and somite formation, complete penetrance	J:118119
Sall4^tm2Tre/Sall4^tm2.1Tre Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * CD-1	embryonic growth arrest	J:115635
	embryonic lethality between implantation and somite formation, complete penetrance	J:115635
Sall4^tm3Ryn/Sall4^tm4Ryn Not Specified	embryonic lethality before implantation, complete penetrance	J:159449

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