Golga2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Golga2
golgin A2
MGI:2139395

48 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Golga2^{tm1(KOMP)Vlcg}/Golga2^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal hepatocyte morphology	J:270564
	abnormal liver morphology	J:270564
	abnormal lung morphology	J:270564
	abnormal surfactant physiology	J:270564
	abnormal type II pneumocyte morphology	J:270564
	decreased body length	J:270564
	decreased body weight	J:270564
	increased alveolar macrophage number	J:270564
	liver fibrosis	J:270564
	prenatal lethality, incomplete penetrance	J:270564
	pulmonary fibrosis	J:270564
Golga2^tm1.1Baos/Golga2^tm1.1Baos Tg(Nes-cre)1Kln/0 involves: 129 * C57BL/6 * SJL	abnormal Golgi apparatus morphology	J:272184
	abnormal Golgi cisterna morphology	J:272184
	abnormal Golgi vesicle transport	J:272184
	abnormal Purkinje cell dendrite morphology	J:272184
	abnormal Purkinje cell morphology	J:272184
	ataxia	J:272184
	decreased Purkinje cell number	J:272184
	impaired coordination	J:272184
	increased neuron apoptosis	J:272184
	limb grasping	J:272184
	normal mortality/aging	J:272184
	postnatal growth retardation	J:272184
	Purkinje cell degeneration	J:272184
	small cerebellum	J:272184
	thin cerebellar molecular layer	J:272184
Golga2^tm1.1Baos/Golga2^tm1.2Baos Tg(Stra8-icre)1Reb/0 involves: 129 * C57BL/6 * FVB/NJ	abnormal sperm head morphology	J:273740
	abnormal sperm mitochondrial sheath morphology	J:273740
	abnormal sperm nucleus morphology	J:273740
	abnormal spermiogenesis	J:273740
	absent acrosome	J:273740
	absent sperm mitochondrial sheath	J:273740
	globozoospermia	J:273740
	male infertility	J:273740
Golga2^tm1.2Baos/Golga2^tm1.2Baos B6.129(Cg)-Golga2^tm1.2Baos	abnormal Golgi apparatus morphology	J:272184
	abnormal Golgi vesicle transport	J:272184
	ataxia	J:272184
	decreased body weight	J:272184
	decreased Purkinje cell number	J:272184
	premature death	J:272184
	slow postnatal weight gain	J:272184
Golga2^tm1.2Baos/Golga2^tm1.2Baos involves: 129 * C57BL/6	abnormal acrosome assembly	J:273740
	abnormal actin cytoskeleton morphology	J:273740
	abnormal cell cytoskeleton morphology	J:273740
	abnormal Golgi apparatus morphology	J:273740
	abnormal microtubule cytoskeleton morphology	J:273740
	abnormal proacrosomal vesicle fusion	J:273740
	abnormal sperm head morphology	J:273740
	abnormal sperm mitochondrial sheath morphology	J:273740
	abnormal sperm nucleus morphology	J:273740
	abnormal spermatid morphology	J:273740
	abnormal spermiogenesis	J:273740
	absent acrosome	J:273740
	absent sperm mitochondrial sheath	J:273740
	decreased body size	J:273740
	decreased body weight	J:273740
	decreased sperm progressive motility	J:273740
	decreased testis weight	J:273740
	globozoospermia	J:273740
	immotile sperm	J:273740
	male infertility	J:273740
	oligozoospermia	J:273740
	premature death	J:273740
	small testis	J:273740

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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