Sec24b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sec24b
SEC24 homolog B, COPII coat complex component
MGI:2139764

29 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sec24b^em1(IMPC)Tcp/Sec24b⁺ C57BL/6NCrl-Sec24b^em1(IMPC)Tcp/Tcp	abnormal eye morphology	J:211773
	enlarged lymph nodes	J:211773
	enlarged spleen	J:211773
Sec24b^em1(IMPC)Tcp/Sec24b^em1(IMPC)Tcp C57BL/6NCrl-Sec24b^em1(IMPC)Tcp/Tcp	abnormal embryo size	J:211773
	abnormal head shape	J:211773
	abnormal tail morphology	J:211773
	exencephaly	J:211773
	preweaning lethality, complete penetrance	J:211773
Sec24b^krb/Sec24b^krb involves: C57BL/6	craniorachischisis	J:158452
Sec24b^krb/Sec24b^krb involves: C57BL/6 * FVB/N	abnormal cardiac outflow tract development	J:158680
	abnormal cochlea morphology	J:158680
	abnormal cochlear inner hair cell morphology	J:158680
	abnormal cochlear outer hair cell morphology	J:158680
	abnormal lung lobe morphology	J:173681
	abnormal neural tube closure	J:158680
	abnormal organ of Corti morphology	J:158680
	abnormal orientation of outer hair cell stereociliary bundles	J:158680
	abnormal visceral yolk sac morphology	J:158680
	craniorachischisis	J:158680, J:173681
	herniated abdominal wall	J:158680
	lethality throughout fetal growth and development, complete penetrance	J:158680
	retroesophageal right subclavian artery	J:158680
	small lung	J:173681
	transposition of great arteries	J:158680
	ventricular hypoplasia	J:158680
Sec24b^m11Bei/Sec24b^m11Bei involves: A/J * C57BL/6	abnormal neural tube morphology	J:199782
Sec24b^Y613X/Sec24b^Y613X involves: C3H/He * C57BL/6	abnormal embryo size	J:158452
	abnormal orientation of inner hair cell stereociliary bundles	J:158452
	abnormal orientation of outer hair cell stereociliary bundles	J:158452
	craniorachischisis	J:158452
	failure of eyelid fusion	J:158452
	lethality throughout fetal growth and development, complete penetrance	J:158452
	omphalocele	J:158452
	open neural tube	J:158452

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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