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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
MGI:2140356
28 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
H6pdtm1a(EUCOMM)Wtsi/H6pdtm1a(EUCOMM)Wtsi
C57BL/6N-H6pdtm1a(EUCOMM)Wtsi/Ics 		decreased body weight J:165965
H6pdtm1c(EUCOMM)Wtsi/H6pdtm1c(EUCOMM)Wtsi
Tg(Adipoq-cre)1Evdr/0
involves: C57BL/6N * FVB/NJ 		abnormal corticosterone level J:292236
normal behavior/neurological phenotype J:292236
normal cardiovascular system phenotype J:292236
decreased circulating free fatty acids level J:292236
decreased circulating insulin level J:292236
decreased epididymal fat pad weight J:292236
decreased fasting circulating glucose level J:292236
decreased fat cell size J:292236
decreased lipogenesis J:292236
decreased mesenteric fat pad weight J:292236
decreased subcutaneous adipose tissue amount J:292236
normal growth/size/body region phenotype J:292236
impaired lipolysis J:292236
improved glucose tolerance J:292236
increased insulin sensitivity J:292236
H6pdtm1Pmst/H6pdtm1Pmst
involves: 129P2/OlaHsd 		abnormal enzyme/coenzyme activity J:141273
abnormal response/metabolism to endogenous compounds J:141273
H6pdtm1Pmst/H6pdtm1Pmst
involves: 129P2/OlaHsd * C57BL/6 		abnormal enzyme/coenzyme activity J:108281
abnormal skeletal muscle fiber morphology J:189132
centrally nucleated skeletal muscle fibers J:189132
decreased body weight J:189132
decreased circulating corticosterone level J:108281, J:189132
decreased circulating glucose level J:189132
decreased lean body mass J:189132
decreased quadriceps weight J:189132
decreased tibialis anterior weight J:189132
enlarged adrenal glands J:108281, J:189132
increased skeletal muscle glycogen level J:189132
skeletal muscle atrophy J:189132
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory