Ppp1r8 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp1r8
protein phosphatase 1, regulatory subunit 8
MGI:2140494

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp1r8^tm1.1Itl/Ppp1r8^tm1Ave Tg(Alb1-cre)7Gsc/0 involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6NTac * FVB/N	abnormal bile duct morphology	J:238108
	abnormal oval cell morphology	J:238108
	abnormal oval cell physiology	J:238108
	bile duct epithelium hyperplasia	J:238108
	bile duct hyperplasia	J:238108
	bile duct proliferation	J:238108
	dilated bile duct	J:238108
	liver inflammation	J:238108
	normal liver/biliary system phenotype	J:238108
Ppp1r8^tm1Ave/Ppp1r8^tm1Ave involves: 129S1/Sv * 129X1/SvJ * Swiss	abnormal developmental patterning	J:91601
	abnormal ectoderm development	J:91601
	abnormal extraembryonic ectoderm morphology	J:91601
	abnormal extraembryonic tissue morphology	J:91601
	abnormal germ layer development	J:91601
	abnormal proamniotic cavity morphology	J:91601
	absent ectoplacental cone	J:91601
	absent mesoderm	J:91601
	absent proamniotic cavity	J:91601
	decreased embryo size	J:91601
	embryonic lethality between implantation and somite formation, complete penetrance	J:91601
	small proamniotic cavity	J:91601

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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