About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Acacb
acetyl-Coenzyme A carboxylase beta
MGI:2140940
28 phenotypes from 4 alleles in 4 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Acacbtm1.1Dejs/Acacbtm1.1Dejs
B6.Cg-Acacbtm1.1Dejs 		abnormal aerobic respiration J:157000
abnormal glucose homeostasis J:157000
abnormal lipid homeostasis J:157000
normal growth/size/body region phenotype J:157000
normal homeostasis/metabolism phenotype J:157000
increased fatty acid oxidation J:157000
increased skeletal muscle glycogen level J:157000
Acacbtm1.1Lowl/Acacbtm1.1Lowl
Tg(Myog-cre)1Eno/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac 		no abnormal phenotype detected J:159285
Acacbtm1.2Lowl/Acacbtm1.2Lowl
involves: 129S6/SvEvTac * FVB/N 		abnormal behavior J:159285
abnormal enzyme/coenzyme level J:159285
decreased respiratory quotient J:159285
normal homeostasis/metabolism phenotype J:159285
increased circulating insulin level J:159285
increased oxygen consumption J:159285
small heart J:159285
Acacbtm1Sjw/Acacbtm1Sjw
Not Specified 		abnormal energy expenditure J:68427
abnormal enzyme/coenzyme level J:68427
abnormal lipid homeostasis J:68427
decreased body weight J:68427
decreased circulating free fatty acids level J:68427
decreased circulating glucose level J:68427
decreased circulating leptin level J:68427
decreased fatty acids level J:68427
decreased liver glycogen level J:68427
decreased liver triglyceride level J:68427
decreased subcutaneous adipose tissue amount J:68427
decreased total body fat amount J:68427
increased circulating ketone body level J:68427
increased circulating triglyceride level J:68427
increased fatty acid beta-oxidation J:68427
increased fatty acid oxidation J:68427
polyphagia J:68427
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory