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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Acacb
acetyl-Coenzyme A carboxylase beta
MGI:2140940
28 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Acacbtm1.1Dejs/Acacbtm1.1Dejs
B6.Cg-Acacbtm1.1Dejs 		abnormal aerobic respiration J:157000
abnormal glucose homeostasis J:157000
abnormal lipid homeostasis J:157000
normal growth/size/body region phenotype J:157000
normal homeostasis/metabolism phenotype J:157000
increased fatty acid oxidation J:157000
increased skeletal muscle glycogen level J:157000
Acacbtm1.1Lowl/Acacbtm1.1Lowl
Tg(Myog-cre)1Eno/0
involves: 129S4/SvJaeSor * 129S6/SvEvTac 		no abnormal phenotype detected J:159285
Acacbtm1.2Lowl/Acacbtm1.2Lowl
involves: 129S6/SvEvTac * FVB/N 		abnormal behavior J:159285
abnormal enzyme/coenzyme level J:159285
decreased respiratory quotient J:159285
normal homeostasis/metabolism phenotype J:159285
increased circulating insulin level J:159285
increased oxygen consumption J:159285
small heart J:159285
Acacbtm1Sjw/Acacbtm1Sjw
Not Specified 		abnormal energy expenditure J:68427
abnormal enzyme/coenzyme level J:68427
abnormal lipid homeostasis J:68427
decreased body weight J:68427
decreased circulating free fatty acids level J:68427
decreased circulating glucose level J:68427
decreased circulating leptin level J:68427
decreased fatty acids level J:68427
decreased liver glycogen level J:68427
decreased liver triglyceride level J:68427
decreased subcutaneous adipose tissue amount J:68427
decreased total body fat amount J:68427
increased circulating ketone body level J:68427
increased circulating triglyceride level J:68427
increased fatty acid beta-oxidation J:68427
increased fatty acid oxidation J:68427
polyphagia J:68427
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory