Prkd2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkd2
protein kinase D2
MGI:2141917

14 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkd2^{em1(IMPC)Hmgu}/Prkd2^{em1(IMPC)Hmgu} C57BL/6N-Prkd2^{em1(IMPC)Hmgu}/Ieg	abnormal brain morphology	J:211773
	decreased food intake	J:211773
	decreased prepulse inhibition	J:211773
	decreased respiratory quotient	J:211773
	decreased startle reflex	J:211773
	increased circulating alanine transaminase level	J:211773
	persistence of hyaloid vascular system	J:211773
Prkd2^{Gt(RRJ380)Byg}/Prkd2^{Gt(RRJ380)Byg} involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:166867
Prkd2^tm1.1Daca/Prkd2^tm1.1Daca involves: C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:166867
	abnormal CD8-positive, alpha-beta T cell physiology	J:166867
	decreased IgG1 level	J:166867
	decreased IgM level	J:166867
	decreased interferon-gamma secretion	J:166867
	decreased interleukin-2 secretion	J:166867
	normal immune system phenotype	J:166867
Prkd2^tm1.1Shoy/Prkd2^tm1.1Shoy Tg(Lck-cre)1Jtak/0 involves: 129 * C57BL/6	normal immune system phenotype	J:236298

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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