Crtc1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Crtc1
CREB regulated transcription coactivator 1
MGI:2142523

27 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Crtc1^Gt(XK522)Byg/Crtc1^Gt(XK522)Byg B6N.129P2-Crtc1^Gt(XK522)Byg	abnormal homeostasis	J:244400
	abnormal nest building behavior	J:244400
	abnormal sexual interaction	J:244400
	abnormal social investigation	J:244400
	anhedonia	J:244400
	behavioral despair	J:244400
	decreased exploration in new environment	J:244400
	decreased serotonin level	J:244400
	impaired cued conditioning behavior	J:244400
	increased aggression towards female mice	J:244400
	increased aggression towards male mice	J:244400
	increased anxiety-related response	J:244400
	social withdrawal	J:244400
Crtc1^Gt(XK522)Byg/Crtc1^Gt(XK522)Byg involves: 129P2/OlaHsd * C57BL/6	absent corpus luteum	J:142448
	decreased circulating luteinizing hormone level	J:142448
	decreased energy expenditure	J:142448
	female infertility	J:142448
	hyperglycemia	J:142448
	impaired glucose tolerance	J:142448
	increased circulating insulin level	J:142448
	increased circulating triglyceride level	J:142448
	increased white adipose tissue amount	J:142448
	male infertility	J:142448
	obese	J:142448
	polyphagia	J:142448
	thin uterus	J:142448
Crtc1^{tm1a(EUCOMM)Wtsi}/Crtc1⁺ C57BL/6N-Crtc1^{tm1a(EUCOMM)Wtsi}/Ics	increased IgG2b level	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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