Nsd3 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nsd3
nuclear receptor binding SET domain protein 3
MGI:2142581

12 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Lyz2^tm1(cre)Ifo/Lyz2⁺ Nsd3^tm1.1Caox/Nsd3^tm1.1Caox involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL	decreased macrophage cytokine production	J:251909
	increased susceptibility to Riboviria infection	J:251909
	increased susceptibility to Riboviria infection induced morbidity/mortality	J:251909
Nsd3^{tm1b(EUCOMM)Hmgu}/Nsd3⁺ C57BL/6N-Nsd3^{tm1b(EUCOMM)Hmgu}/H	increased total body fat amount	J:211773
	tremors	J:211773
	trunk curl	J:211773
Nsd3^{tm1b(EUCOMM)Hmgu}/Nsd3^{tm1b(EUCOMM)Hmgu} C57BL/6N-Nsd3^{tm1b(EUCOMM)Hmgu}/H	abnormal snout morphology	J:211773
	decreased exploration in new environment	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased startle reflex	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	small spleen	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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