Il20rb Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il20rb
interleukin 20 receptor beta
MGI:2143266

18 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il20rb^em2(IMPC)Mbp/Il20rb^em2(IMPC)Mbp C57BL/6N-Il20rb^em2(IMPC)Mbp/Ucd	abnormal epididymis morphology	J:211773
	abnormal eye morphology	J:211773
	decreased prepulse inhibition	J:211773
	enlarged epididymis	J:211773
	increased circulating alanine transaminase level	J:211773
Il20rb^{tm1b(KOMP)Wtsi}/Il20rb⁺ C57BL/6N-Il20rb^{tm1b(KOMP)Wtsi}/Ucd	enlarged epididymis	J:211773
Il20rb^{tm1b(KOMP)Wtsi}/Il20rb^{tm1b(KOMP)Wtsi} C57BL/6N-Il20rb^{tm1b(KOMP)Wtsi}/Ucd	abnormal brain morphology	J:211773
	hydrocephaly	J:211773
	increased circulating alanine transaminase level	J:211773
Il20rb^tm1Dnax/Il20rb^tm1Dnax B6.129-Il20rb^tm1Dnax	abnormal response/metabolism to endogenous compounds	J:124591
Il20rb^tm1Lex/Il20rb^tm1Lex involves: 129	no abnormal phenotype detected	J:161073
Il20rb^tm1Uwe/Il20rb^tm1Uwe B6.129P2-Il20rb^tm1Uwe	abnormal cytotoxic T cell physiology	J:143497
	abnormal T-helper 1 physiology	J:143497
	decreased interleukin-4 secretion	J:143497
	decreased interleukin-10 secretion	J:143497
	increased interferon-gamma secretion	J:143497
	increased interleukin-2 secretion	J:143497
	increased memory T cell number	J:143497
	increased T cell proliferation	J:143497
Il20rb^tm1Uwe/Il20rb^tm1Uwe C.129P2-Il20rb^tm1Uwe	increased susceptibility to type IV hypersensitivity reaction	J:143497

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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