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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Traf3ip2
TRAF3 interacting protein 2
MGI:2143599
45 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cd40tm1Kik/Cd40tm1Kik
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
involves: 129 * 129P2/OlaHsd * BALB/c 		abnormal B cell physiology J:138560
enlarged lymph nodes J:93923
enlarged spleen J:93923
normal immune system phenotype J:138560
increased follicular B cell number J:138560
increased marginal zone B cell number J:138560
increased transitional stage B cell number J:138560
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2+
involves: 129 * 129S4/SvJae * C57BL/6 		abnormal neutrophil morphology J:191090
abnormal T cell morphology J:191090
decreased survivor rate J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased autoantibody level J:191090
increased double-negative T cell number J:191090
increased IgG level J:191090
increased memory T cell number J:191090
increased monocyte cell number J:191090
increased myeloid dendritic cell number J:191090
increased neutrophil cell number J:191090
increased plasma cell number J:191090
increased plasmacytoid dendritic cell number J:191090
increased single-positive T cell number J:191090
increased spleen germinal center number J:191090
increased susceptibility to systemic lupus erythematosus J:191090
kidney inflammation J:191090
premature death J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm1Sbn/Traf3ip2tm1Sbn
involves: 129 * 129S4/SvJae * C57BL/6 		abnormal T cell morphology J:191090
decreased survivor rate J:191090
decreased susceptibility to systemic lupus erythematosus J:191090
increased anti-double stranded DNA antibody level J:191090
increased anti-nuclear antigen antibody level J:191090
increased autoantibody level J:191090
increased double-negative T cell number J:191090
increased IgG level J:191090
premature death J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm2Sbn/Traf3ip2+
involves: 129S4/SvJae * BALB/c * C57BL/6 		enlarged spleen J:191090
increased germinal center B cell number J:191090
increased plasma cell number J:191090
increased spleen weight J:191090
spleen hyperplasia J:191090
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Traf3ip2tm2Sbn/Traf3ip2tm2Sbn
Cd79atm1(cre)Reth/Cd79a+
involves: 129S4/SvJae * BALB/c * C57BL/6 		glomerulonephritis J:191090
increased germinal center B cell number J:191090
increased plasma cell number J:191090
Tcrbtm1Mom/Tcrbtm1Mom
Tcrdtm1Mom/Tcrdtm1Mom
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
B6.129-Tcrbtm1Mom Traf3ip2tm1.1Lix Tcrdtm1Mom 		abnormal glomerular capillary morphology J:187766
abnormal transitional stage B cell morphology J:187766
decreased IgG level J:187766
decreased T cell number J:187766
normal immune system phenotype J:187766
increased anti-chromatin antibody level J:187766
increased anti-double stranded DNA antibody level J:187766
increased anti-histone antibody level J:187766
increased autoantibody level J:187766
increased IgM level J:187766
increased immature B cell number J:187766
increased marginal zone B cell number J:187766
increased mesangial cell number J:187766
renal glomerular immunoglobulin deposits J:187766
Traf3ip2tm1.1Lix/Traf3ip2tm1.1Lix
Tnfsf13btm1Msc/Tnfsf13btm1Msc
involves: 129 * 129S2/SvPas * BALB/c 		decreased B cell number J:138560
decreased follicular B cell number J:138560
decreased mature B cell number J:138560
decreased transitional stage B cell number J:138560
enlarged lymph nodes J:93923
enlarged spleen J:93923
increased autoantibody level J:138560
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory