Psme4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Psme4
proteasome (prosome, macropain) activator subunit 4
MGI:2143994

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Psme4^b2b1508Clo/Psme4^b2b1508Clo C57BL/6J-Psme4^b2b1508Clo	abnormal liver morphology	J:175213
	atrioventricular septal defect	J:175213
	d-loop transposition of the great arteries	J:175213
	dextrocardia	J:175213
	double outlet right ventricle, Taussig bing type	J:175213
	dual inferior vena cava	J:175213
	heterotaxia	J:175213
	mesocardia	J:175213
	muscular ventricular septal defect	J:175213
	right aortic arch	J:175213
	right pulmonary isomerism	J:175213
	thymus hypoplasia	J:175213
	tricuspid valve atresia	J:175213
Psme4^tm1Slek/Psme4^tm1Slek involves: 129 * C57BL/6	abnormal male germ cell morphology	J:107376
	abnormal spermatid morphology	J:107376
	abnormal spermatocyte morphology	J:107376
	abnormal spermatogenesis	J:107376
	asthenozoospermia	J:107376
	multinucleated giant male germ cells	J:107376
	reduced male fertility	J:107376
	teratozoospermia	J:107376
Psme4^tm1Tchi/Psme4^tm1Tchi involves: C57BL/6	abnormal spermatid morphology	J:197675
	increased male germ cell apoptosis	J:197675
	reduced male fertility	J:197675

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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