Ppif Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppif
peptidylprolyl isomerase F (cyclophilin F)
MGI:2145814

10 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppif^tm1.1Mmos/Ppif⁺ involves: 129X1/SvJ * FVB/NJ	decreased cerebral infarct size	J:101149
Ppif^tm1.1Mmos/Ppif^tm1.1Mmos involves: 129X1/SvJ * FVB/NJ	abnormal mitochondrial physiology	J:101149
	decreased cerebral infarct size	J:101149
	normal nervous system phenotype	J:101149
Ppif^tm1Jmol/Ppif^tm1Jmol involves: 129	abnormal mitochondrial physiology	J:97660
Ppif^tm1Jmol/Ppif^tm1Jmol involves: 129	decreased myocardial infarct size	J:97660
Ppif^tm1Maf/Ppif^tm1Maf B6.129-Ppif^tm1Maf	abnormal mitochondrial physiology	J:99922
Ppif^tm1Tsu/Ppif^tm1Tsu involves: 129S5/SvEvBrd	abnormal mitochondrial physiology	J:97673
	decreased cellular sensitivity to hydrogen peroxide	J:97673
	decreased myocardial infarct size	J:97673
	decreased sensitivity to induced cell death	J:157346
Tg(Myh6-Ppif)26.2Jmol/0 FVB/N-Tg(Myh6-Ppif)26.2Jmol	abnormal mitochondrial crista morphology	J:97660
	abnormal myocardial fiber mitochondrial morphology	J:97660
	dilated mitochondrion	J:97660
	increased apoptosis	J:97660

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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