Prkaa1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
MGI:2145955

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Prkaa1^tm1.1Mfor/Prkaa1^tm1.1Mfor Prkaa2^tm1Vio/Prkaa2^tm1Vio involves: 129S2/SvPas	normal homeostasis/metabolism phenotype	J:174020
Prkaa1^tm1.1Sjm/Prkaa1^tm1.1Sjm Prkaa2^tm1.1Sjm/Prkaa2^tm1.1Sjm Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA * SJL	normal cellular phenotype	J:165090
	decreased hematopoietic stem cell number	J:165090
	normal hematopoietic system phenotype	J:165090
	increased mitochondrial fission	J:165090
Prkaa1^tm1Sbj/Prkaa1⁺ Prkaa2^tm1Vio/Prkaa2^tm1Vio involves: 129S2/SvPas * FVB/N	increased body weight	J:123951
	increased susceptibility to diet-induced obesity	J:123951
Prkaa1^tm1Sbj/Prkaa1^tm1Sbj Prkaa2^tm1.1Vio/Prkaa2^tm1.1Vio involves: 129S2/SvPas	normal cellular phenotype	J:141132
Prkaa1^tm1Sbj/Prkaa1^tm1Sbj Prkaa2^tm1Vio/Prkaa2^tm1Vio Tg(Pomc1-cre)1Gsb/0 involves: 129S2/SvPas * FVB/N	increased body weight	J:123951

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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