Mtbp Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
MGI:2146005

6 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mtbp^tm1Glo/Mtbp⁺ Trp53^tm1Tyj/Trp53⁺ involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	decreased tumor-free survival time	J:135509
	increased leukemia incidence	J:135509
	increased lymphoma incidence	J:135509
	increased metastatic potential	J:135509
	increased tumor incidence	J:135509
Mtbp^tm1Glo/Mtbp^tm1Glo Trp53^tm1Tyj/Trp53⁺ involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	embryonic lethality between implantation and somite formation, complete penetrance	J:135509
Mtbp^tm1Glo/Mtbp^tm1Glo Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	embryonic lethality between implantation and somite formation, complete penetrance	J:135509

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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