Alg10b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Alg10b
ALG10 alpha-1,2-glucosyltransferase
MGI:2146159

32 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alg10b^nse5/Alg10b^nse5 129S6.B6-Alg10b^nse5	abnormal cochlear outer hair cell morphology	J:209766
	absent cochlear microphonics	J:209766
	absent distortion product otoacoustic emissions	J:209766
	cochlear outer hair cell degeneration	J:209766
	deafness	J:209766
	decreased cochlear outer hair cell number	J:209766
	normal hearing/vestibular/ear phenotype	J:209766
	increased or absent threshold for auditory brainstem response	J:209766
Alg10b^nse5/Alg10b^nse5 involves: C57BL/6J	deafness	J:85113
Alg10b^{tm1(KOMP)Vlcg}/Alg10b⁺ C57BL/6N-Alg10b^{tm1(KOMP)Vlcg}/Bay	increased body temperature	J:211773
Alg10b^{tm1(KOMP)Vlcg}/Alg10b^{tm1(KOMP)Vlcg} C57BL/6N-Alg10b^{tm1(KOMP)Vlcg}/Bay	preweaning lethality, complete penetrance	J:211773
Alg10b^{tm1.1(KOMP)Vlcg}/Alg10b^{tm1.1(KOMP)Vlcg} C57BL/6N-Alg10b^{tm1.1(KOMP)Vlcg}/Bay	abnormal allantois morphology	J:211773
	abnormal embryo development	J:211773
	abnormal embryo size	J:211773
	abnormal forebrain development	J:211773
	abnormal heart morphology	J:211773
	abnormal hindbrain development	J:211773
	abnormal limb bud morphology	J:211773
	abnormal midbrain development	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	abnormal optic vesicle formation	J:211773
	abnormal otic vesicle morphology	J:211773
	abnormal pericardium morphology	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal somite shape	J:211773
	abnormal visceral yolk sac morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	bleb	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	pale yolk sac	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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