Dock10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dock10
dedicator of cytokinesis 10
MGI:2146320

25 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dock10^{tm1a(EUCOMM)Hmgu}/Dock10^{tm1a(EUCOMM)Hmgu} C57BL/6N-Dock10^{tm1a(EUCOMM)Hmgu}/Ieg	abnormal B cell physiology	J:236911
	abnormal behavior	J:165965
	abnormal follicular B cell physiology	J:236911
	abnormal spleen marginal zone morphology	J:238172
	abnormal thymus cell ratio	J:238172
	arrested B cell differentiation	J:236911
	decreased B cell number	J:236911
	decreased follicular B cell number	J:236911
	decreased hemoglobin content	J:165965
	decreased marginal zone B cell number	J:236911
	normal growth/size/body region phenotype	J:238172
	normal immune system phenotype	J:238172
	increased hematocrit	J:165965
	increased hemoglobin content	J:165965
	increased single-positive T cell number	J:236911
	increased T cell number	J:236911
	normal mortality/aging	J:238172
	normal reproductive system phenotype	J:238172
Dock10^tm1Thar/Dock10^tm1Thar involves: C57BL/6	abnormal astrocyte physiology	J:300632
	abnormal microglial cell chemotaxis	J:300632
	normal behavior/neurological phenotype	J:300632
	decreased B cell number	J:300632
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:300632
	impaired macrophage chemotaxis	J:300632
	normal nervous system phenotype	J:300632
	normal vision/eye phenotype	J:300632

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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