About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ift140
intraflagellar transport 140
MGI:2146906
88 phenotypes from 4 alleles in 6 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Ift140b2b1283Clo/Ift140b2b1283Clo
C57BL/6J-Ift140b2b1283Clo 		abnormal aortic arch morphology J:175213
absent spleen J:175213
atrioventricular septal defect J:175213
cleft palate J:175213
kidney cyst J:175213
left pulmonary isomerism J:175213
persistent truncus arteriosus J:175213
polydactyly J:175213
right aortic arch J:175213
Ift140cauli/Ift140cauli
involves: C3H/HeH * C57BL/6JAnu 		abnormal atrioventricular valve morphology J:220659
abnormal costovertebral joint morphology J:220659
abnormal craniofacial morphology J:199856, J:220659
abnormal digit morphology J:220659
abnormal exoccipital bone morphology J:220659
abnormal heart looping J:199856
abnormal heart ventricle morphology J:220659
abnormal interventricular septum morphology J:220659
abnormal limb bud morphology J:220659
abnormal lung morphology J:220659
abnormal maxilla morphology J:220659
abnormal mouth morphology J:220659
abnormal neural tube closure J:220659
abnormal neural tube morphology J:220659
abnormal primary cilium morphology J:220659
abnormal rib morphology J:220659
abnormal somite development J:220659
abnormal tricuspid valve morphology J:220659
absent alisphenoid bone J:220659
absent facial bone J:220659
absent neurocranium J:220659
absent palatine bone J:220659
absent tympanic ring J:220659
anophthalmia J:199856, J:220659
cervical vertebral fusion J:220659
curly tail J:220659
exencephaly J:199856, J:220659
exostosis J:220659
facial bone hypoplasia J:220659
forelimb oligodactyly J:199856, J:220659
fusion of atlas and occipital bones J:220659
heart hemorrhage J:220659
hydrops fetalis J:220659
lethality throughout fetal growth and development, complete penetrance J:220659
lethality throughout fetal growth and development, incomplete penetrance J:199856
maxilla hypoplasia J:220659
omphalocele J:220659
palatal shelf hypoplasia J:220659
polydactyly J:199856, J:220659
premaxilla hypoplasia J:220659
prenatal growth retardation J:220659
rib bifurcation J:220659
spina bifida J:199856
Ift140tm1b(KOMP)Wtsi/Ift140tm1b(KOMP)Wtsi
B6.B6N-Ift140tm1b(KOMP)Wtsi 		embryonic lethality, complete penetrance J:181533
Ift140tm1b(KOMP)Wtsi/Ift140tm1b(KOMP)Wtsi
involves: C57BL/6N 		abnormal hindlimb bud morphology J:220659
abnormal mouth morphology J:220659
embryonic lethality during organogenesis, complete penetrance J:220659
exencephaly J:220659
Ift140tm1b(KOMP)Wtsi/Ift140tm1c(KOMP)Wtsi
Tg(Hoxb7-cre)13Amc/?
B6J.B6-Ift140tm1b(KOMP)Wtsi/Ift140tm1c(Komp)Wtsi Tg(Hoxb7-cre)13Amc 		abnormal kidney collecting duct morphology J:181533
abnormal kidney morphology J:181533
abnormal kidney physiology J:181533
normal cellular phenotype J:181533
decreased kidney epithelial cell primary cilium length J:181533
dilated kidney collecting duct J:181533
increased kidney apoptosis J:181533
increased kidney cell proliferation J:181533
kidney cortex cyst J:181533
kidney cyst J:181533
kidney failure J:181533
kidney medulla cyst J:181533
renal fibrosis J:181533
Ift140tm1c(KOMP)Wtsi/Ift140tm1c(KOMP)Wtsi
Tg(Stra8-icre)1Reb/0
involves: C57BL/6N * FVB/NJ 		abnormal manchette morphology J:285527
abnormal outer dense fiber morphology J:285527
abnormal sperm axoneme morphology J:285527
abnormal sperm end piece morphology J:285527
abnormal sperm fibrous sheath morphology J:285527
abnormal sperm flagellum morphology J:285527
abnormal sperm head morphology J:285527
abnormal sperm mitochondrial morphology J:285527
abnormal sperm nucleus morphology J:285527
abnormal spermatid morphology J:285527
abnormal spermiation J:285527
abnormal spermiogenesis J:285527
asthenozoospermia J:285527
decreased sperm progressive motility J:285527
immotile sperm J:285527
impaired fertilization J:285527
kinked sperm flagellum J:285527
male infertility J:285527
oligozoospermia J:285527
normal reproductive system phenotype J:285527
short sperm flagellum J:285527
teratozoospermia J:285527
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory