Fbxo11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fbxo11
F-box protein 11
MGI:2147134

43 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fbxo11^Jf/Fbxo11⁺ involves: BALB/cAnNCrl	abnormal pinna reflex	J:250208
	normal hearing/vestibular/ear phenotype	J:250208
	impaired hearing	J:250208
	increased susceptibility to otitis media	J:250208
	middle ear effusion	J:250208
	middle ear polyps	J:250208
Fbxo11^Jf/Fbxo11⁺ involves: BALB/cAnNCrl * C3H/HeN	abnormal auditory tube morphology	J:85263
	abnormal cytokine secretion	J:85263
	abnormal middle ear ossicle morphology	J:85263
	abnormal tympanic cavity morphology	J:85263
	absent pinna reflex	J:85263
	deafness	J:63816, J:85263
	decreased body size	J:85263
	decreased body weight	J:85263
	decreased endocochlear potential	J:85263
	excessive cerumen	J:85263
	normal hearing/vestibular/ear phenotype	J:85263
	increased susceptibility to otitis media	J:85263
	middle ear effusion	J:85263
	middle ear polyps	J:85263
	short snout	J:85263
	tympanic membrane retraction	J:85263
Fbxo11^Jf/Fbxo11⁺ involves: BALB/cAnNCrl * C3H/HeN * C57BL/6J	increased susceptibility to otitis media	J:114851
Fbxo11^Jf/Fbxo11^Jf involves: BALB/cAnNCrl * C3H/HeN	cleft palate	J:114851
	eyelids open at birth	J:114851
	midline facial cleft	J:114851
	neonatal lethality, complete penetrance	J:114851
Fbxo11^Jf/Fbxo11^Mutt involves: BALB/c * C3H/HeN	impaired hearing	J:114851
	increased susceptibility to otitis media	J:114851
	midline facial cleft	J:114851
	neonatal lethality, incomplete penetrance	J:114851
	short face	J:114851
Fbxo11^Mutt/Fbxo11⁺ involves: BALB/c * C3H/HeN	decreased startle reflex	J:114851
Fbxo11^Mutt/Fbxo11⁺ involves: BALB/c * C3H/HeN	short face	J:114851
Fbxo11^Mutt/Fbxo11^Mutt involves: BALB/c * C3H/HeN	cleft palate	J:114851
	impaired hearing	J:114851
	midline facial cleft	J:114851
	perinatal lethality, incomplete penetrance	J:114851
	short face	J:114851
Fbxo11^{tm2a(EUCOMM)Wtsi}/Fbxo11^{tm2a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal protein level	J:220308
	absent keratohyalin granules	J:220308
	decreased hair follicle number	J:220308
	epidermal hyperplasia	J:220308
	neonatal lethality, complete penetrance	J:220308
	thick epidermis	J:220308
Fbxo11^{tm2b(EUCOMM)Wtsi}/Fbxo11⁺ C57BL/6N-Fbxo11^{tm2b(EUCOMM)Wtsi}/H	decreased circulating calcium level	J:211773
	decreased circulating iron level	J:211773
	decreased circulating total protein level	J:211773
	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	decreased hemoglobin content	J:211773
	hyperactivity	J:211773
	increased fasting circulating glucose level	J:211773
	increased red blood cell distribution width	J:211773
	narrow eye opening	J:211773
	short tibia	J:211773
Fbxo11^{tm2b(EUCOMM)Wtsi}/Fbxo11^{tm2b(EUCOMM)Wtsi} C57BL/6N-Fbxo11^{tm2b(EUCOMM)Wtsi}/H	preweaning lethality, complete penetrance	J:211773

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