Tnfaip8 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnfaip8
tumor necrosis factor, alpha-induced protein 8
MGI:2147191

13 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Tnfaip8^{Gt(IST13629C1)Tigm}/Tnfaip8^{Gt(IST13629C1)Tigm} involves: C57BL/6N	abnormal colon morphology	J:223320
	normal digestive/alimentary phenotype	J:223320
	normal immune system phenotype	J:223320
	increased circulating interleukin-6 level	J:223320
	increased circulating interleukin-17 level	J:223320
	increased enterocyte apoptosis	J:223320
	increased interleukin-1 beta secretion	J:223320
	increased interleukin-6 secretion	J:223320
	increased interleukin-17 secretion	J:223320
	increased neutrophil cell number	J:223320
	increased susceptibility to induced colitis	J:223320
	increased susceptibility to weight loss	J:223320
	small spleen	J:223320

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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