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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Marveld1
MARVEL (membrane-associating) domain containing 1
MGI:2147570
24 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Marveld1tm1.1Liy/Marveld1tm1.1Liy
Tg(GFAP-cre)25Mes/0
involves: C57BL/6J * FVB/N 		abnormal cerebellar granule cell migration J:279065
abnormal cerebellar Purkinje cell layer J:279065
abnormal CNS glial cell morphology J:279065
abnormal Purkinje cell dendrite morphology J:279065
Marveld1tm1.1Liy/Marveld1tm1.1Liy
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * C57BL/6J * SJL 		abnormal cerebellar granule cell migration J:279065
abnormal CNS glial cell morphology J:279065
abnormal Purkinje cell dendrite morphology J:279065
abnormal Purkinje cell morphology J:279065
Marveld1tm1.2Liy/Marveld1tm1.2Liy
involves: C57BL/6J 		abnormal Bergmann glial cell morphology J:279065
abnormal cerebellar granule cell migration J:279065
abnormal cerebellar layer morphology J:279065
abnormal cerebellar Purkinje cell layer J:279065
abnormal CNS glial cell morphology J:279065
abnormal dendrite morphology J:279065
abnormal gait J:279065
abnormal locomotor activation J:279065
abnormal neuronal migration J:279065
abnormal posture J:279065
abnormal Purkinje cell dendrite morphology J:279065
abnormal Purkinje cell morphology J:279065
abnormal stratification in cerebral cortex J:279065
abnormal synapse morphology J:279065
decreased neuron number J:279065
impaired coordination J:279065
impaired spatial learning J:279065
impaired swimming J:279065
increased neuron apoptosis J:279065
increased thermal nociceptive threshold J:279065
neuron degeneration J:279065
Purkinje cell degeneration J:279065
short stride length J:279065
thin external granule cell layer J:279065
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory