Ffar4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ffar4
free fatty acid receptor 4
MGI:2147577

35 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ffar4^{tm1(KOMP)Vlcg}/Ffar4^{tm1(KOMP)Vlcg} involves: C57BL/6NTac	abnormal beige fat cell physiology	J:240649
	abnormal brown adipose tissue physiology	J:240649
	abnormal brown fat cell differentiation	J:240649
	abnormal white adipose tissue morphology	J:240649
	abnormal white adipose tissue physiology	J:240649
	abnormal white fat cell differentation	J:240649
	decreased oxygen consumption	J:240649
	decreased physiological sensitivity to xenobiotic	J:240649
	impaired adaptive thermogenesis	J:240649
Ffar4^tm1.1Mbj/Ffar4^tm1.1Mbj involves: C57BL/6	abnormal insulin secretion	J:211675
Ffar4^tm1.1Mbj/Ffar4^tm1.1Mbj involves: C57BL/6	abnormal pancreatic somatostatin secretion	J:211675
Ffar4^tm1Gdds/Ffar4^tm1Gdds involves: 129 * C57BL/6	abnormal lipid level	J:182599
	decreased energy expenditure	J:182599
	decreased respiratory quotient	J:182599
	enlarged pancreatic islets	J:182599
	hepatic steatosis	J:182599
	impaired glucose tolerance	J:182599
	increased circulating alanine transaminase level	J:182599
	increased circulating cholesterol level	J:182599
	increased circulating glucose level	J:182599
	increased circulating HDL cholesterol level	J:182599
	increased circulating insulin level	J:182599
	increased circulating LDL cholesterol level	J:182599
	increased circulating leptin level	J:182599
	increased liver triglyceride level	J:182599
	increased liver weight	J:182599
	increased susceptibility to diet-induced obesity	J:182599
	increased total body fat amount	J:182599
	increased white adipose tissue amount	J:182599
	increased white fat cell size	J:182599
	insulin resistance	J:182599
Ffar4^tm1Lex/Ffar4^tm1Lex involves: 129S/SvEvBrd * C57BL/6 * C57BL/6J	normal homeostasis/metabolism phenotype	J:200805
Ffar4^tm1Sdmk/Ffar4^tm1Sdmk C57BL/6J-Ffar4^tm1Sdmk	abnormal gustatory system physiology	J:161517
	abnormal sensory neuron physiology	J:161517
	abnormal taste sensitivity	J:161517

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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