Tle6 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tle6
transducin-like enhancer of split 6
MGI:2149593

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nlrp5^tm1Zbt/Nlrp5^tm1Zbt Ooep^{Gt(139A2)Cmhd}/Ooep^{Gt(139A2)Cmhd} Tle6^tm1Lil/Tle6^tm1Lil involves: 129S1/Sv * 129X1/SvJ	abnormal mitotic spindle morphology	J:276268
	failure of zygotic cell division	J:276268
Tg(RP23-352G18)1Coppa/0 C57BL/6-Tg(RP23-352G18)1Coppa	decreased circulating glucose level	J:229077
	decreased susceptibility to diet-induced non-insulin dependent diabetes	J:229077
	decreased susceptibility to diet-induced obesity	J:229077
	improved glucose tolerance	J:229077
	increased insulin sensitivity	J:229077

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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