Gopc Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gopc
golgi associated PDZ and coiled-coil motif containing
MGI:2149946

19 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gopc^tm1.1Tno/Gopc^tm1.1Tno involves: 129S4/SvJae	abnormal sperm flagellum morphology	J:124177
	coiled sperm flagellum	J:124177
	globozoospermia	J:124177
Gopc^tm1.1Tno/Gopc^tm1.1Tno involves: 129S4/SvJae * C57BL/6	abnormal acrosome morphology	J:78599
	abnormal sperm mitochondrial sheath morphology	J:78599
	abnormal sperm nucleus morphology	J:78599
	abnormal spermatogenesis	J:78599
	absent acrosome	J:78599
	asthenozoospermia	J:78599
	coiled sperm flagellum	J:78599
	detached acrosome	J:78599
	globozoospermia	J:78599
	impaired fertilization	J:78599
	male infertility	J:78599
Gopc^{tm1a(EUCOMM)Wtsi}/Gopc^{tm1a(EUCOMM)Wtsi} C57BL/6-Gopc^{tm1a(EUCOMM)Wtsi}	abnormal cell physiology	J:232679
	prenatal lethality, incomplete penetrance	J:232679
Gopc^{tm1e.1(EUCOMM)Wtsi}/Gopc⁺ C57BL/6N-Gopc^{tm1e.1(EUCOMM)Wtsi}/Tcp	abnormal cecum morphology	J:211773
	decreased circulating calcium level	J:211773
	enlarged cecum	J:211773
	increased circulating phosphate level	J:211773
Gopc^{tm1e.1(EUCOMM)Wtsi}/Gopc^{tm1e.1(EUCOMM)Wtsi} C57BL/6N-Gopc^{tm1e.1(EUCOMM)Wtsi}/Tcp	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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