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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tmc2
transmembrane channel-like gene family 2
MGI:2151017
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tmc1tm1.1Ajg/Tmc1+
Tmc2tm1.1Ajg/Tmc2tm1.1Ajg
B6.129-Tmc2tm1.1Ajg Tmc1tm1.1Ajg 		abnormal vestibuloocular dark reflex J:184419
Tmc1tm1.1Ajg/Tmc1tm1.1Ajg
Tmc2tm1.1Ajg/Tmc2+
B6.129-Tmc2tm1.1Ajg Tmc1tm1.1Ajg 		abnormal hair cell mechanoelectric transduction J:184419
Tmc1tm1.1Ajg/Tmc1tm1.1Ajg
Tmc2tm1.1Ajg/Tmc2tm1.1Ajg
B6.129-Tmc2tm1.1Ajg Tmc1tm1.1Ajg 		abnormal cochlear hair cell physiology J:184419
abnormal hair cell mechanoelectric transduction J:184419
abnormal hair cell physiology J:184419
abnormal vestibuloocular dark reflex J:184419
ataxia J:184419
circling J:184419
cochlear hair cell degeneration J:184419
cochlear inner hair cell degeneration J:184419
cochlear outer hair cell degeneration J:184419
deafness J:184419
head bobbing J:184419
impaired righting response J:184419
increased or absent threshold for auditory brainstem response J:184419
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory