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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Stim2
stromal interaction molecule 2
MGI:2151156
33 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Stim1tm1.1Rao/Stim1tm1.1Rao
Stim2tm1.1Rao/Stim2tm1.1Rao
involves: C57BL/6 		decreased cellular sensitivity to hydrogen peroxide J:175075
Stim1tm1Kuro/Stim1tm1Kuro
Stim2tm1.1Kuro/Stim2tm1.1Kuro
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c * C57BL/6 		abnormal B cell calcium ion homeostasis J:172608
abnormal B cell physiology J:172608
decreased B cell proliferation J:172608
decreased interleukin-10 secretion J:172608
demyelination J:172608
normal immune system phenotype J:172608
increased CD4-positive, alpha-beta T cell number J:172608
increased CD8-positive, alpha-beta T cell number J:172608
increased interferon-gamma secretion J:172608
increased interleukin-10 secretion J:172608
increased interleukin-17 secretion J:172608
increased regulatory T cell number J:172608
increased susceptibility to experimental autoimmune encephalomyelitis J:172608
Stim1tm1Rao/Stim1tm1Rao
Stim2tm1Rao/Stim2tm1Rao
Tg(Cd4-cre)1Cwi/0
involves: C57BL/6 * DBA/2 * SJL 		abnormal B cell differentiation J:133262
abnormal CD4-positive, alpha-beta T cell physiology J:133262
abnormal granulocyte morphology J:133262
abnormal immune system morphology J:133262
abnormal immune system physiology J:133262
abnormal lymph organ size J:133262
abnormal T cell differentiation J:133262
blepharitis J:133262
decreased interferon-gamma secretion J:133262
decreased interleukin-2 secretion J:133262
decreased regulatory T cell number J:133262
decreased T cell proliferation J:133262
dermatitis J:133262
enlarged lymph nodes J:133262
enlarged spleen J:133262
increased germinal center B cell number J:133262
increased IgG1 level J:133262
increased lymphocyte cell number J:133262
increased spleen germinal center number J:133262
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory