Tgs1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tgs1
trimethylguanosine synthase 1
MGI:2151797

9 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tgs1^tm1.1Jkr/Tgs1^tm1.1Jkr involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J	abnormal cell cycle	J:189008
	impaired fibroblast cell migration	J:189008
Tgs1^tm1.2Jkr/Tgs1^tm1.2Jkr involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N	abnormal blastocyst morphology	J:189008
	abnormal embryonic tissue physiology	J:189008
	abnormal inner cell mass morphology	J:189008
	decreased embryo size	J:189008
	embryonic growth arrest	J:189008
	embryonic lethality between implantation and somite formation, complete penetrance	J:189008
	failure of blastocyst to hatch from the zona pellucida	J:189008

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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