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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
MGI:2152214
32 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pip4k2ctm1b(KOMP)Wtsi/Pip4k2ctm1b(KOMP)Wtsi
C57BL/6N-Pip4k2ctm1b(KOMP)Wtsi/J 		abnormal auditory brainstem response J:211773
hyperactivity J:211773
increased fasting circulating glucose level J:211773
Pip4k2ctm1b(KOMP)Wtsi/Pip4k2ctm1b(KOMP)Wtsi
involves: C57BL/6J * C57BL/6N 		abnormal circulating chemokine level J:234283
abnormal circulating protein level J:234283
abnormal T cell activation J:234283
chronic inflammation J:234283
chronic liver inflammation J:234283
decreased blood urea nitrogen level J:234283
decreased regulatory T cell number J:234283
normal growth/size/body region phenotype J:234283
normal homeostasis/metabolism phenotype J:234283
increased CD4-positive, alpha-beta T cell number J:234283
increased CD8-positive, alpha-beta T cell number J:234283
increased circulating aspartate transaminase level J:234283
increased circulating interferon-gamma level J:234283
increased circulating interleukin-2 level J:234283
increased circulating interleukin-4 level J:234283
increased circulating interleukin-10 level J:234283
increased circulating interleukin-12 level J:234283
increased circulating interleukin-12b level J:234283
increased IgG3 level J:234283
increased inflammatory response J:234283
increased interferon-gamma secretion J:234283
increased interleukin-17 secretion J:234283
increased T cell proliferation J:234283
increased T-helper cell number J:234283
intestinal inflammation J:234283
kidney inflammation J:234283
lung inflammation J:234283
pale liver J:234283
salivary gland inflammation J:234283
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory