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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Taf4b
TATA-box binding protein associated factor 4b
MGI:2152345
35 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Taf4btm1Rtj/Taf4btm1Rtj
B6.129-Taf4btm1Rtj 		abnormal acrosome assembly J:97245
abnormal spermatogenesis J:97245
abnormal spermatogonia proliferation J:97245
abnormal spermiogenesis J:97245
asthenozoospermia J:97245
decreased male germ cell number J:97245
decreased testis weight J:97245
early reproductive senescence J:97245
increased circulating follicle stimulating hormone level J:97245
increased Leydig cell number J:97245
male infertility J:97245
oligozoospermia J:97245
seminiferous tubule degeneration J:97245
small testis J:97245
Taf4btm1Rtj/Taf4btm1Rtj
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal estrous cycle J:156655
abnormal oocyte morphology J:71679, J:156655
abnormal superovulation J:71679
abnormal tertiary ovarian follicle number J:119191
absent mature ovarian follicles J:71679
absent ovarian follicles J:156655
decreased granulosa cell proliferation J:119191
decreased oocyte number J:156655
decreased primordial ovarian follicle number J:119191
decreased secondary ovarian follicle number J:119191
decreased tertiary ovarian follicle number J:119191
early sexual maturation J:156655
female infertility J:71679
impaired ovarian folliculogenesis J:71679, J:119191
increased atretic ovarian follicle number J:119191
increased circulating follicle stimulating hormone level J:156655
increased granulosa cell apoptosis J:119191
ovary cyst J:156655
ovary degeneration J:156655
premature ovarian failure J:156655
prolonged estrus J:156655
small ovary J:71679
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory