Gsk3a Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gsk3a
glycogen synthase kinase 3 alpha
MGI:2152453

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^tm1Tno/Apc^tm1Tno Gsk3a^tm1Jrw/Gsk3a^tm1Jrw Gsk3b^tm2Jrw/Gsk3b^tm2Jrw involves: 129 * C57BL/6 * CBA	abnormal urinary bladder urothelium morphology	J:164579
Gsk3a^tm1.1Tac/Gsk3a^tm1.1Tac Tg(APPV717F)109Ili/0 Tg(Camk2a-cre)#Stl/0 involves: BALB/c * C57BL * C57BL/6NTac	amyloid beta deposits	J:184975
	normal behavior/neurological phenotype	J:184975
Gsk3a^{tm1a(EUCOMM)Wtsi}/Gsk3a⁺ Gsk3b^tm1Grc/Gsk3b⁺ involves: 129S6/SvEvTac * C57BL/6N	cleft palate	J:195008
Gsk3a^{tm1a(EUCOMM)Wtsi}/Gsk3a⁺ Gsk3b^tm1Grc/Gsk3b^tm1Grc involves: 129S6/SvEvTac * C57BL/6N	cleft palate	J:195008
Gsk3a^tm1Dral/Gsk3a^tm1Dral Gsk3b^tm1Dral/Gsk3b^tm1Dral involves: 129P2/OlaHsd	abnormal behavioral response to xenobiotic	J:200517
	abnormal long-term depression	J:200517
	decreased coping response	J:200517
	enhanced contextual conditioning behavior	J:200517
	hyperactivity	J:200517
	impaired cued conditioning behavior	J:200517
	increased anxiety-related response	J:200517
	increased circulating corticosterone level	J:200517
	increased circulating interleukin-6 level	J:200517
	increased exploration in new environment	J:200517
	increased thigmotaxis	J:200517
Gsk3a^tm1Dral/Gsk3a^tm1Dral Gsk3b^tm1Dral/Gsk3b^tm1Dral involves: 129P2/OlaHsd * C57BL/6 * CBA	normal homeostasis/metabolism phenotype	J:98263
	increased liver glycogen level	J:98263
Gsk3a^tm1Dral/Gsk3a^tm1Dral Gsk3b^tm1Dral/Gsk3b^tm1Dral Gys1^tm1.1Arte/Gys1^tm1.1Arte involves: 129P2/OlaHsd * C57BL/6J	abnormal glycogen homeostasis	J:167911

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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