Rims1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rims1
regulating synaptic membrane exocytosis 1
MGI:2152971

18 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rims1^tm1Sud/Rims1^tm1Sud involves: 129P2/OlaHsd	abnormal excitatory postsynaptic currents	J:106269
	abnormal inhibitory postsynaptic currents	J:143053
	abnormal paired-pulse inhibition	J:143053
	disorganized barrel cortex	J:106269
	impaired synaptic plasticity	J:106269
Rims1^tm1Sud/Rims1^tm1Sud involves: 129P2/OlaHsd * C57BL/6	abnormal CNS synaptic transmission	J:73900
	abnormal excitatory postsynaptic potential	J:73900
	abnormal long-term depression	J:73899
	abnormal maternal nurturing	J:73900
	abnormal paired-pulse facilitation	J:73900
	abnormal post-tetanic potentiation	J:73900
	decreased paired-pulse facilitation	J:73900
	enhanced paired-pulse facilitation	J:73900
	reduced long-term potentiation	J:73899
Rims1^tm2Sud/Rims1^tm2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	normal behavior/neurological phenotype	J:142749
	normal nervous system phenotype	J:142749
Rims1^tm3.1Sud/Rims1^tm3.1Sud involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	postnatal lethality, incomplete penetrance	J:143053
Rims1^tm3.1Sud/Rims1^tm3.1Sud involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal inhibitory postsynaptic currents	J:143053
	abnormal paired-pulse inhibition	J:143053
	enhanced paired-pulse facilitation	J:143053
	impaired synaptic plasticity	J:143053
	postnatal lethality	J:143053
Rims1^tm3Sud/Rims1^tm3Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal inhibitory postsynaptic currents	J:143053

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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