Rims1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rims1
regulating synaptic membrane exocytosis 1
MGI:2152971

18 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rims1^tm1Sud/Rims1^tm1Sud involves: 129P2/OlaHsd	abnormal excitatory postsynaptic currents	J:106269
	abnormal inhibitory postsynaptic currents	J:143053
	abnormal paired-pulse inhibition	J:143053
	disorganized barrel cortex	J:106269
	impaired synaptic plasticity	J:106269
Rims1^tm1Sud/Rims1^tm1Sud involves: 129P2/OlaHsd * C57BL/6	abnormal CNS synaptic transmission	J:73900
	abnormal excitatory postsynaptic potential	J:73900
	abnormal long-term depression	J:73899
	abnormal maternal nurturing	J:73900
	abnormal paired-pulse facilitation	J:73900
	abnormal post-tetanic potentiation	J:73900
	decreased paired-pulse facilitation	J:73900
	enhanced paired-pulse facilitation	J:73900
	reduced long-term potentiation	J:73899
Rims1^tm2Sud/Rims1^tm2Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	normal behavior/neurological phenotype	J:142749
	normal nervous system phenotype	J:142749
Rims1^tm3.1Sud/Rims1^tm3.1Sud involves: 129P2/OlaHsd * 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	postnatal lethality, incomplete penetrance	J:143053
Rims1^tm3.1Sud/Rims1^tm3.1Sud involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal inhibitory postsynaptic currents	J:143053
	abnormal paired-pulse inhibition	J:143053
	enhanced paired-pulse facilitation	J:143053
	impaired synaptic plasticity	J:143053
	postnatal lethality	J:143053
Rims1^tm3Sud/Rims1^tm3Sud involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal inhibitory postsynaptic currents	J:143053

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24