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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cspg4
chondroitin sulfate proteoglycan 4
MGI:2153093
27 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cspg4tm1(cre)Akik/Cspg4tm1(cre)Akik
involves: C57BL/6N 		normal nervous system phenotype J:171287
Cspg4tm1.1(cre/ERT2)Fki/Cspg4+
involves: 129P2/OlaHsd * C57BL/6N 		no abnormal phenotype detected J:209130
Cspg4tm1Wbst/Cspg4tm1Wbst
involves: 129S1/Sv * 129X1/SvJ 		abnormal adipose tissue development J:184220
abnormal brown adipose tissue morphology J:184220
abnormal macrophage physiology J:184220
decreased body temperature J:184220
decreased carbon dioxide production J:184220
decreased oxygen consumption J:184220
decreased white fat cell number J:184220
hepatic steatosis J:184220
impaired adaptive thermogenesis J:184220
impaired glucose tolerance J:184220
increased body weight J:184220
increased circulating cholesterol level J:184220
increased circulating HDL cholesterol level J:184220
increased circulating LDL cholesterol level J:184220
increased epididymal fat pad weight J:184220
increased gonadal fat pad weight J:184220
increased susceptibility to age related obesity J:184220
insulin resistance J:184220
obese J:184220
Cspg4tm1Wbst/Cspg4tm1Wbst
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal cell migration J:54319
abnormal dentate gyrus morphology J:114437
abnormal enzyme/coenzyme activity J:54319
decreased cell proliferation J:54319
normal nervous system phenotype J:114437
Cspg4tm1Ychan/Cspg4tm1Ychan
Olig2tm2(TVA,cre)Rth/Olig2+
involves: 129 * C57BL/6N 		decreased body weight J:184220
decreased epididymal fat pad weight J:184220
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory