About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
MGI:2153480
34 phenotypes from 3 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Atp6v0a4m1Anu/Atp6v0a4m1Anu
C57BL/6NCrlAnu-Atp6v0a4m1Anu 		premature death J:104190
Atp6v0a4tm1(KOMP)Vlcg/Atp6v0a4tm1(KOMP)Vlcg
C57BL/6N-Atp6v0a4tm1(KOMP)Vlcg/Rbrc 		preweaning lethality, complete penetrance J:211773
Atp6v0a4tm1.1Fekf/Atp6v0a4+
involves: C57BL/6 		acidosis J:188593
decreased bone mineral density J:188593
hydronephrosis J:188593
Atp6v0a4tm1.1Fekf/Atp6v0a4tm1.1Fekf
involves: C57BL/6 		abnormal inner ear morphology J:188593
abnormal motor coordination/balance J:188593
abnormal renal tubule morphology J:188593
abnormal sensory capabilities/reflexes/nociception J:188593
abnormal urine homeostasis J:188593
absent endocochlear potential J:188593
absent otoliths J:188593
absent pinna reflex J:188593
acidosis J:188593
circling J:188593
cystolithiasis J:188593
decreased body size J:188593
decreased body weight J:188593
decreased urine pH J:188593
dehydration J:188593
dilated endolymphatic duct J:188593
dilated scala media J:188593
head tilt J:188593
normal homeostasis/metabolism phenotype J:188593
hydronephrosis J:188593
hypokalemia J:188593
impaired hearing J:188593
impaired olfaction J:188593
increased blood osmolality J:188593
increased blood urea nitrogen level J:188593
increased circulating chloride level J:188593
increased or absent threshold for auditory brainstem response J:188593
nephrocalcinosis J:188593
polydipsia J:188593
polyuria J:188593
postnatal lethality, incomplete penetrance J:188593
premature death J:188593
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory