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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
MGI:2153480
34 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atp6v0a4m1Anu/Atp6v0a4m1Anu
C57BL/6NCrlAnu-Atp6v0a4m1Anu 		premature death J:104190
Atp6v0a4tm1(KOMP)Vlcg/Atp6v0a4tm1(KOMP)Vlcg
C57BL/6N-Atp6v0a4tm1(KOMP)Vlcg/Rbrc 		preweaning lethality, complete penetrance J:211773
Atp6v0a4tm1.1Fekf/Atp6v0a4+
involves: C57BL/6 		acidosis J:188593
decreased bone mineral density J:188593
hydronephrosis J:188593
Atp6v0a4tm1.1Fekf/Atp6v0a4tm1.1Fekf
involves: C57BL/6 		abnormal inner ear morphology J:188593
abnormal motor coordination/balance J:188593
abnormal renal tubule morphology J:188593
abnormal sensory capabilities/reflexes/nociception J:188593
abnormal urine homeostasis J:188593
absent endocochlear potential J:188593
absent otoliths J:188593
absent pinna reflex J:188593
acidosis J:188593
circling J:188593
cystolithiasis J:188593
decreased body size J:188593
decreased body weight J:188593
decreased urine pH J:188593
dehydration J:188593
dilated endolymphatic duct J:188593
dilated scala media J:188593
head tilt J:188593
normal homeostasis/metabolism phenotype J:188593
hydronephrosis J:188593
hypokalemia J:188593
impaired hearing J:188593
impaired olfaction J:188593
increased blood osmolality J:188593
increased blood urea nitrogen level J:188593
increased circulating chloride level J:188593
increased or absent threshold for auditory brainstem response J:188593
nephrocalcinosis J:188593
polydipsia J:188593
polyuria J:188593
postnatal lethality, incomplete penetrance J:188593
premature death J:188593
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory