Plxnb1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plxnb1
plexin B1
MGI:2154238

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Pax8^{tm1.1(cre)Mbu}/Pax8⁺ Plxnb1^tm1Rkun/Plxnb1^tm1Rkun Plxnb2^tm1.1Rkun/Plxnb2^tm1.1Rkun involves: 129P2/OlaHsd * C57BL/6	abnormal renal tubule epithelium morphology	J:221423
Plxnb1^tm1.1Ltam/Plxnb1⁺ Plxnb2^tm1Matl/Plxnb2⁺ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	normal mortality/aging	J:168399
	reduced fertility	J:168399
Plxnb1^tm1.1Ltam/Plxnb1⁺ Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	embryonic lethality	J:168399
Plxnb1^tm1.1Ltam/Plxnb1^tm1.1Ltam Plxnb2^tm1Matl/Plxnb2⁺ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	normal mortality/aging	J:168399
	reduced fertility	J:168399
Plxnb1^tm1.1Ltam/Plxnb1^tm1.1Ltam Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	abnormal ureteric bud trunk morphology	J:168399
	embryonic lethality	J:168399
	renal hypoplasia	J:168399
Plxnb1^tm1Matl/Plxnb1^tm1Matl Plxnb2^{tm1c(EUCOMM)Wtsi}/Plxnb2^tm1Matl Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal cerebellar lobule formation	J:228347
	abnormal cerebral cortex morphology	J:228347
	abnormal cortical ventricular zone morphology	J:228347
	absent corpus callosum	J:228347
	decreased corpus callosum size	J:228347
	decreased neuronal precursor cell number	J:228347
	decreased neuronal precursor proliferation	J:228347
	ectopic cerebellar granule cells	J:228347
	enlarged lateral ventricles	J:228347
	normal nervous system phenotype	J:228347
	premature neuronal precursor differentiation	J:228347
	thin cerebral cortex	J:228347

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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