Plxnb2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plxnb2
plexin B2
MGI:2154239

56 phenotypes from 6 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pax8^{tm1.1(cre)Mbu}/Pax8⁺ Plxnb2^tm1.1Rkun/Plxnb2^tm1.1Rkun involves: 129P2/OlaHsd * C57BL/6	abnormal renal tubule epithelium morphology	J:221423
	increased susceptibility to kidney reperfusion injury	J:221423
Plxnb2^m597804Hubr/Plxnb2^m597804Hubr involves: C57BL/6 * FVB/N	abnormal neural tube morphology	J:173681
	exencephaly	J:173681
Plxnb2^{tm1a(EUCOMM)Wtsi}/Plxnb2⁺ C57BL/6N-Plxnb2^{tm1a(EUCOMM)Wtsi}/Ieg	abnormal urination	J:165965
	increased body weight	J:165965
Plxnb2^{tm1a(EUCOMM)Wtsi}/Plxnb2^{tm1a(EUCOMM)Wtsi} C57BL/6-Plxnb2^{tm1a(EUCOMM)Wtsi}	abnormal coat/hair pigmentation	J:167973
	belly spot	J:167973
Plxnb2^{tm1c(EUCOMM)Wtsi}/Plxnb2^tm1Matl Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * C57BL/6N * SJL	abnormal cerebellar lobule formation	J:228347
	abnormal neuronal precursor cell migration	J:228347
	abnormal olfactory bulb development	J:228347
	abnormal rostral migratory stream morphology	J:228347
	ectopic cerebellar granule cells	J:228347
	normal nervous system phenotype	J:228347
Plxnb2^tm1Matl/Plxnb2^tm1Matl B6.129P2-Plxnb2^tm1Matl	abnormal cerebellar granule cell migration	J:167973
Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd	normal vision/eye phenotype	J:172268
Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd * C57BL/6	abnormal ureteric bud tip morphology	J:168399
	curly tail	J:119485
	double kidney pelvis	J:168399
	double ureter	J:168399
	duplex kidney	J:168399
	exencephaly	J:119485
	impaired branching involved in ureteric bud morphogenesis	J:168399
	incomplete caudal neuropore closure	J:119485
	incomplete rostral neuropore closure	J:119485
	neonatal lethality, incomplete penetrance	J:119485
	renal hypoplasia	J:168399
	small kidney	J:168399
	spina bifida	J:119485
Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd * C57BL/6 * CD-1	belly spot	J:167973
Plxnb2^tm1Matl/Plxnb2^tm1Matl involves: 129P2/OlaHsd * CD-1	abnormal cerebellar cortex morphology	J:119485
	abnormal cerebellar foliation	J:119485
	abnormal cerebellar granule layer morphology	J:119485
	abnormal cerebellar Purkinje cell layer	J:119485
	abnormal cerebellum external granule cell layer morphology	J:119485
	abnormal cerebellum morphology	J:119485
	abnormal neuronal precursor cell migration	J:190014
	abnormal olfactory bulb granule cell morphology	J:190014
	abnormal olfactory bulb internal plexiform layer morphology	J:190014
	abnormal olfactory bulb interneuron morphology	J:190014
	abnormal olfactory bulb layer morphology	J:190014
	abnormal olfactory bulb mitral cell layer morphology	J:190014
	abnormal olfactory bulb periglomerular cell morphology	J:190014
	abnormal radial glial cell morphology	J:119485
	abnormal rostral migratory stream morphology	J:190014
	normal behavior/neurological phenotype	J:119485
	decreased neuronal precursor proliferation	J:190014
	ectopic cerebellar granule cells	J:119485
	ectopic Purkinje cell	J:119485
	neonatal lethality, incomplete penetrance	J:119485
	normal reproductive system phenotype	J:119485
	small cerebellum	J:119485
Plxnb2^tm1Rkun/Plxnb2^tm1Rkun involves: FVB/N	abnormal brain morphology	J:121970
	abnormal brain ventricle morphology	J:121970
	abnormal cerebellar foliation	J:121970
	abnormal cerebellar granule cell morphology	J:121970
	abnormal cerebellum external granule cell layer morphology	J:121970
	abnormal choroid plexus morphology	J:121970
	abnormal diencephalon morphology	J:121970
	abnormal olfactory bulb development	J:121970
	abnormal striatum morphology	J:121970
	absent cerebellar foliation	J:121970
	enlarged brain ventricles	J:121970
	exencephaly	J:121970
	open neural tube	J:121970
	prenatal lethality, complete penetrance	J:121970
	spina bifida	J:121970

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