Plxnd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plxnd1
plexin D1
MGI:2154244

75 phenotypes from 8 alleles in 15 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plxnd1^b2b553Clo/Plxnd1^b2b553Clo C57BL/6J-Plxnd1^b2b553Clo	abnormal inferior vena cava morphology	J:175213
	absent kidney	J:175213
	atrium cyst	J:175213
	complete atrioventricular septal defect	J:175213
	double outlet right ventricle	J:175213
	dual inferior vena cava	J:175213
	persistent truncus arteriosus	J:175213
	persistent truncus arteriosus type i	J:175213
	persistent truncus arteriosus type ii	J:175213
	renal glomerulus cyst	J:175213
	right aortic arch	J:175213
Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo C57BL/6J-Plxnd1^b2b1863Clo	absent kidney	J:175213
	atrioventricular septal defect	J:175213
	cleft palate	J:175213
	double outlet right ventricle	J:175213
	dual inferior vena cava	J:175213
	persistent truncus arteriosus type ii	J:175213
	right aortic arch	J:175213
	thymus hypoplasia	J:175213
Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo C57BL/6J-Plxnd1^b2b3150Clo	abnormal left subclavian artery morphology	J:175213
	absent kidney	J:175213
	atrioventricular septal defect	J:175213
	cleft palate	J:175213
	common atrium	J:175213
	micrognathia	J:175213
	persistent truncus arteriosus	J:175213
	right aortic arch	J:175213
	short snout	J:175213
	thymus hypoplasia	J:175213
	vascular ring	J:175213
	ventricular septal defect	J:175213
Plxnd1^em1Zho/Plxnd1⁺ C57BL/6-Plxnd1^em1Zho	abnormal ventricle myocardium morphology	J:326461
	atrial septal defect	J:326461
	thin myocardium	J:326461
	ventricular septal defect	J:326461
Plxnd1^em1Zho/Plxnd1^em1Zho C57BL/6-Plxnd1^em1Zho	abnormal coronary sinus connection	J:326461
	abnormal lung interstitium morphology	J:326461
	abnormal lung vasculature morphology	J:326461
	abnormal pulmonary vein morphology	J:326461
	abnormal vascular endothelial cell migration	J:326461
	abnormal ventricle myocardium morphology	J:326461
	atelectasis	J:326461
	atrial septal defect	J:326461
	decreased fetal size	J:326461
	enhanced wound healing	J:326461
	increased angiogenesis	J:326461
	increased capillary density	J:326461
	persistent truncus arteriosus	J:326461
	prenatal lethality, incomplete penetrance	J:326461
	subcutaneous hemorrhage	J:326461
	thin myocardium	J:326461
	ventricular septal defect	J:326461
Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * CBA/J	normal cardiovascular system phenotype	J:143763
	normal mortality/aging	J:143763
Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj Tg(CAG-cre/Esr1)5Amc/0 involves: 129S/SvEv 129S4/SvJaeSor * C57BL/6 * CBA	abnormal retina vasculature morphology	J:143763
	abnormal vascular endothelial cell migration	J:143763
	decreased angiogenesis	J:143763
	hemorrhage	J:143763
Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj Tg(Nes-cre)1Atp/0 involves: 129S/SvEv * FVB/N	normal vision/eye phenotype	J:172268
Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * SJL	abnormal aorta morphology	J:143763
	abnormal blood vessel morphology	J:143763
	abnormal coronary vessel morphology	J:143763
	abnormal heart atrium morphology	J:143763
	abnormal intersomitic vessel morphology	J:143763
	abnormal myocardium layer morphology	J:143763
	abnormal truncus arteriosus septation	J:143763
	abnormal vertebral body morphology	J:143763
	cyanosis	J:143763
	decreased body height	J:143763
	detached epicardium	J:143763
	dilated heart atrium	J:143763
	fusion of vertebral bodies	J:143763
	hemorrhage	J:143763
	intracranial hemorrhage	J:143763
	neonatal lethality, incomplete penetrance	J:143763
	persistent truncus arteriosus	J:143763
	postnatal lethality, complete penetrance	J:143763
	rib fusion	J:143763
	right aortic arch	J:143763
	short tail	J:143763
	ventricular septal defect	J:143763
Plxnd1^tm1.1Vlcg/Plxnd1^tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac	no abnormal phenotype detected	J:200671
Plxnd1^tm1Ddg/Plxnd1^tm1.1Tmj H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S/SvEv * C57BL/6 * C57BL/6J * CBA/J	abnormal motor neuron innervation pattern	J:149553
	abnormal motor neuron morphology	J:149553
	normal behavior/neurological phenotype	J:149553
Plxnd1^tm1Ddg/Plxnd1^tm1.1Tmj H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ involves: 129S/SvEv * C57BL/6J * CBA/J	abnormal excitatory postsynaptic potential	J:205528
	normal nervous system phenotype	J:205528
Plxnd1^tm1Ddg/Plxnd1^tm1.1Tmj Tg(CAG-cre/Esr1)1Egwa/0 involves: 129S/SvEv C57BL/6 * DBA/2	abnormal induced retina neovascularization	J:173943
Plxnd1^tm1Ddg/Plxnd1^tm1Ddg involves: 129S/SvEv * C57BL/6J	abnormal intersomitic vessel morphology	J:95697
Plxnd1^tm1Joe/Plxnd1^tm1Joe involves: 129S1/Sv * 129X1/SvJ	abnormal vascular endothelial cell migration	J:143763
	abnormal vertebral body morphology	J:143763
	fusion of vertebral bodies	J:143763
Plxnd1^tm1Joe/Plxnd1^tm1Joe involves: 129S1/Sv * 129X1/SvJ * C57BL/6	aberrant origin of the right subclavian artery	J:91658
	abnormal artery morphology	J:91658
	abnormal ascending aorta and coronary artery attachment	J:91658
	abnormal fourth pharyngeal arch artery morphology	J:91658
	abnormal heart atrium morphology	J:91658
	abnormal intersomitic vessel morphology	J:91658
	abnormal left subclavian artery morphology	J:91658
	abnormal sixth pharyngeal arch artery morphology	J:91658
	abnormal vascular smooth muscle morphology	J:91658
	absent fetal ductus arteriosus	J:91658
	cyanosis	J:91658
	increased angiogenesis	J:91658
	increased heart atrium size	J:91658
	neonatal lethality, complete penetrance	J:91658
	persistent truncus arteriosus	J:91658
	right aortic arch	J:91658

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