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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sec63
SEC63 homolog, protein translocation regulator
MGI:2155302
8 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pkd1tm1Som/Pkd1+
Sec63tm1Som/Sec63tm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		abnormal loop of Henle ascending limb thick segment morphology J:188763
dilated kidney collecting duct J:188763
increased blood urea nitrogen level J:188763
increased kidney apoptosis J:188763
increased kidney cell proliferation J:188763
increased kidney weight J:188763
kidney cyst J:188763
Pkd2tm2Som/Pkd2+
Sec63tm1Som/Sec63tm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
kidney cyst J:188763
Prkcshtm1Som/Prkcshtm1Som
Sec63tm1.1Som/Sec63tm1.1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * ICR 		liver cyst J:188763
Sec63tm1Som/Sec63tm1Som
Tg(Pkd1)248Som/0
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL/J 		kidney cyst J:188763
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory