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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Myh7
myosin, heavy polypeptide 7, cardiac muscle, beta
MGI:2155600
17 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Myh7em1Dsr/Myh7+
involves: C57BL/6J 		no abnormal phenotype detected J:277399
Myh7em1Dsr/Myh7em1Dsr
involves: C57BL/6J 		congestive heart failure J:277399
embryonic lethality during organogenesis, complete penetrance J:277399
Tg(Myh6-Myh7)102Rbns/?
involves: FVB/N 		abnormal cardiovascular system physiology J:119670
abnormal myocardial fiber physiology J:128692
Tg(Myh6-Myh7)102Rbns/Tg(Myh6-Myh7)102Rbns
involves: FVB/N 		abnormal heart atrium morphology J:166125
abnormal heart left ventricle morphology J:166125
abnormal physiological response to xenobiotic J:166125
abnormal response to cardiac infarction J:166125
normal cardiovascular system phenotype J:166125
decreased cardiac muscle contractility J:166125
decreased left ventricle systolic pressure J:166125
decreased systemic arterial systolic blood pressure J:166125
increased heart left ventricle weight J:166125
increased heart right ventricle weight J:166125
increased lung weight J:166125
Tg(Myh6-Myh7)137Rbns/0
involves: FVB/N 		abnormal heart atrium morphology J:166125
abnormal heart left ventricle morphology J:166125
abnormal physiological response to xenobiotic J:166125
abnormal response to cardiac infarction J:166125
decreased cardiac muscle contractility J:166125
decreased left ventricle systolic pressure J:166125
decreased systemic arterial systolic blood pressure J:166125
increased heart left atrium size J:166125
increased heart left ventricle weight J:166125
increased heart right ventricle weight J:166125
increased lung weight J:166125
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory