Il25 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il25
interleukin 25
MGI:2155888

38 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il25^em1(IMPC)Mbp/Il25^em1(IMPC)Mbp C57BL/6NCrl-Il25^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged testis	J:211773
	microphthalmia	J:211773
	prolonged QRS complex duration	J:211773
	small testis	J:211773
Il25^tm1.1Cdon/Il25^tm1.1Cdon involves: 129S6/SvEvTac	abnormal chemokine secretion	J:229778
	abnormal colon morphology	J:229778
	abnormal interleukin secretion	J:229778
	decreased eosinophil cell number	J:229778
	decreased interleukin-1 beta secretion	J:229778
	decreased interleukin-4 secretion	J:158594, J:229778
	decreased interleukin-5 secretion	J:158594, J:229778
	decreased interleukin-9 secretion	J:158594
	decreased interleukin-13 secretion	J:158594, J:229778
	decreased susceptibility to bacterial infection	J:229778
	decreased susceptibility to induced colitis	J:229778
	decreased susceptibility to weight loss	J:229778
	decreased T-helper 2 cell number	J:229778
	decreased tumor necrosis factor secretion	J:229778
	increased susceptibility to type I hypersensitivity reaction	J:158594
	lung inflammation	J:158594
Il25^tm1Anjm/Il25^tm1Anjm involves: 129P2/OlaHsd * C57BL/6	abnormal interleukin secretion	J:123748
	abnormal mesenteric lymph node morphology	J:123748
	decreased eosinophil cell number	J:123748
	decreased interleukin-5 secretion	J:123748
	decreased interleukin-13 secretion	J:123748
	increased IgE level	J:123748
	increased susceptibility to parasitic infection	J:123748
Il25^tm1Cdon/Il25^tm1Cdon Tg(Vil1-cre)997Gum/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL	abnormal colon morphology	J:229778
	decreased susceptibility to induced colitis	J:229778
	decreased susceptibility to weight loss	J:229778
Il25^tm1Dart/Il25^tm1Dart C57BL/6-Il25^tm1Dart	abnormal crypts of Lieberkuhn morphology	J:123808
	abnormal interferon level	J:123808
	abnormal interleukin level	J:123808
	abnormal intestinal goblet cell morphology	J:123808
	abnormal response to infection	J:123808
	decreased IgG2a level	J:123808
	increased susceptibility to parasitic infection	J:123808
	intestinal inflammation	J:123808
Il25^tm1Dart/Il25^tm1Dart involves: C57BL/6	abnormal interleukin level	J:125296
	increased susceptibility to experimental autoimmune encephalomyelitis	J:125296
	increased susceptibility to induced morbidity/mortality	J:125296
	increased T cell number	J:125296
Il25^tm1Lex/Il25^tm1Lex B6;129S5-Il25^tm1Lex/Orl	increased circulating triglyceride level	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24