Il25 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il25
interleukin 25
MGI:2155888

38 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il25^em1(IMPC)Mbp/Il25^em1(IMPC)Mbp C57BL/6NCrl-Il25^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal testis morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	enlarged testis	J:211773
	microphthalmia	J:211773
	prolonged QRS complex duration	J:211773
	small testis	J:211773
Il25^tm1.1Cdon/Il25^tm1.1Cdon involves: 129S6/SvEvTac	abnormal chemokine secretion	J:229778
	abnormal colon morphology	J:229778
	abnormal interleukin secretion	J:229778
	decreased eosinophil cell number	J:229778
	decreased interleukin-1 beta secretion	J:229778
	decreased interleukin-4 secretion	J:158594, J:229778
	decreased interleukin-5 secretion	J:158594, J:229778
	decreased interleukin-9 secretion	J:158594
	decreased interleukin-13 secretion	J:158594, J:229778
	decreased susceptibility to bacterial infection	J:229778
	decreased susceptibility to induced colitis	J:229778
	decreased susceptibility to weight loss	J:229778
	decreased T-helper 2 cell number	J:229778
	decreased tumor necrosis factor secretion	J:229778
	increased susceptibility to type I hypersensitivity reaction	J:158594
	lung inflammation	J:158594
Il25^tm1Anjm/Il25^tm1Anjm involves: 129P2/OlaHsd * C57BL/6	abnormal interleukin secretion	J:123748
	abnormal mesenteric lymph node morphology	J:123748
	decreased eosinophil cell number	J:123748
	decreased interleukin-5 secretion	J:123748
	decreased interleukin-13 secretion	J:123748
	increased IgE level	J:123748
	increased susceptibility to parasitic infection	J:123748
Il25^tm1Cdon/Il25^tm1Cdon Tg(Vil1-cre)997Gum/0 involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * SJL	abnormal colon morphology	J:229778
	decreased susceptibility to induced colitis	J:229778
	decreased susceptibility to weight loss	J:229778
Il25^tm1Dart/Il25^tm1Dart C57BL/6-Il25^tm1Dart	abnormal crypts of Lieberkuhn morphology	J:123808
	abnormal interferon level	J:123808
	abnormal interleukin level	J:123808
	abnormal intestinal goblet cell morphology	J:123808
	abnormal response to infection	J:123808
	decreased IgG2a level	J:123808
	increased susceptibility to parasitic infection	J:123808
	intestinal inflammation	J:123808
Il25^tm1Dart/Il25^tm1Dart involves: C57BL/6	abnormal interleukin level	J:125296
	increased susceptibility to experimental autoimmune encephalomyelitis	J:125296
	increased susceptibility to induced morbidity/mortality	J:125296
	increased T cell number	J:125296
Il25^tm1Lex/Il25^tm1Lex B6;129S5-Il25^tm1Lex/Orl	increased circulating triglyceride level	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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