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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tiparp
TCDD-inducible poly(ADP-ribose) polymerase
MGI:2159210
53 phenotypes from 2 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
decreased circulating estradiol level J:142042
decreased litter size J:142042
enlarged ovary J:142042
enlarged uterus J:142042
increased corpora lutea number J:142042
increased tertiary ovarian follicle number J:142042
long gestation period J:142042
ovary cyst J:142042
prolonged estrous cycle J:142042
reduced female fertility J:142042
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
involves: 129S4/SvJaeSor
abnormal blood vessel morphology J:117491
abnormal frontal bone morphology J:117491
abnormal kidney morphology J:117491
abnormal neurocranium morphology J:117491
abnormal palate morphology J:117491
abnormal renal glomerulus morphology J:117491
abnormal skeleton morphology J:117491
abnormal smooth muscle morphology J:117491
abnormal sternum morphology J:117491
anemia J:117491
asymmetric sternocostal joints J:117491
broad snout J:117491
decreased erythrocyte cell number J:117491
decreased hematocrit J:117491
decreased hemoglobin content J:117491
decreased palatine bone horizontal plate size J:117491
hemorrhage J:117491
increased blood urea nitrogen level J:117491
kidney inflammation J:117491
pale kidney J:117491
polychromatophilia J:117491
postnatal lethality J:117491
reticulocytosis J:117491
short maxilla J:117491
short nasal bone J:117491
short premaxilla J:117491
short snout J:117491
small kidney J:117491
small presphenoid bone J:117491
TiparpGt(ROSA)79Sor/TiparpGt(ROSA)79Sor
involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J
abnormal thymus involution J:250417
decreased fasting circulating glucose level J:250417
enlarged liver J:250417
hepatic steatosis J:250417
increased circulating alanine transaminase level J:250417
increased physiological sensitivity to xenobiotic J:250417
increased susceptibility to weight loss J:250417
increased susceptibility to xenobiotic induced morbidity/mortality J:250417
liver degeneration J:250417
Tiparptm1b(EUCOMM)Wtsi/Tiparp+
C57BL/6N-Tiparptm1b(EUCOMM)Wtsi/Tcp
abnormal skin morphology J:211773
scaly skin J:211773
Tiparptm1b(EUCOMM)Wtsi/Tiparptm1b(EUCOMM)Wtsi
C57BL/6N-Tiparptm1b(EUCOMM)Wtsi/Tcp
abnormal spleen morphology J:211773
enlarged spleen J:211773
preweaning lethality, incomplete penetrance J:211773

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory