Asic3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Asic3
acid-sensing ion channel 3
MGI:2159339

33 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Asic3^em1(IMPC)Mbp/Asic3^em1(IMPC)Mbp C57BL/6NCrl-Asic3^em1(IMPC)Mbp/MbpMmucd	abnormal auditory brainstem response	J:211773
	abnormal gallbladder morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased body length	J:211773
	decreased prepulse inhibition	J:211773
	enlarged gallbladder	J:211773
	enlarged spleen	J:211773
	small liver	J:211773
Asic3^tm1Pho/Asic3^tm1Pho B6.Cg-Acic3^tm1Pho	abnormal brainstem morphology	J:151304
Asic3^tm1Pho/Asic3^tm1Pho involves: C57BL/6	abnormal eye electrophysiology	J:151049
	abnormal retina apoptosis	J:151049
	abnormal rod electrophysiology	J:151049
	abnormal sensory neuron morphology	J:151049
	amacrine cell degeneration	J:151049
	disorganized retina inner nuclear layer	J:151049
	disorganized retina outer nuclear layer	J:151049
	photoreceptor inner segment degeneration	J:151049
	photoreceptor outer segment degeneration	J:151049
	retina ganglion cell degeneration	J:151049
	retina outer nuclear layer degeneration	J:151049
	thin retina outer plexiform layer	J:151049
Asic3^tm1Pig/Asic3^tm1Pig involves: 129/Sv * CD-1	abnormal mechanical nociception	J:81785
	normal behavior/neurological phenotype	J:81785
	decreased chemical nociceptive threshold	J:81785
	decreased thermal nociceptive threshold	J:81785
	hyperresponsive to tactile stimuli	J:81785
	normal nervous system phenotype	J:81785
Asic3^tm1Wsh/Asic3^tm1Wsh B6.129-Asic3^tm1Wsh	abnormal mechanical nociception	J:128319
Asic3^tm1Wsh/Asic3^tm1Wsh B6.129-Asic3^tm1Wsh	abnormal physiological response to xenobiotic	J:128319
Asic3^tm1Wsh/Asic3^tm1Wsh involves: 129S1/Sv * 129X1/SvJ	abnormal nervous system electrophysiology	J:119060
Asic3^tm1Wsh/Asic3^tm1Wsh involves: 129S1/Sv * 129X1/SvJ	hyporesponsive to tactile stimuli	J:119060
Asic3^tm1Wsh/Asic3^tm1Wsh involves: 129S1/Sv * 129X1/SvJ * C57BL	hyperalgesia	J:73505
	increased or absent threshold for auditory brainstem response	J:89141

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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