Agtpbp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agtpbp1
ATP/GTP binding protein 1
MGI:2159437

64 phenotypes from 14 alleles in 19 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agtpbp1^atms/Agtpbp1^atms MRL/Mp-Agtpbp1^atms	abnormal lymphocyte cell number	J:103944
	abnormal spleen morphology	J:103944
	abnormal T cell differentiation	J:103944
	abnormal T cell physiology	J:103944
	abnormal T cell subpopulation ratio	J:103944
	ataxia	J:103944
	decreased B cell number	J:103944
	decreased spleen weight	J:103944
	increased CD4-positive, alpha-beta T cell number	J:103944
	increased CD8-positive, alpha-beta T cell number	J:103944
	spleen hypoplasia	J:103944
Agtpbp1^atms/Agtpbp1^atms MRL/Mp-Agtpbp1^atms Fas^lpr	ataxia	J:103944
Agtpbp1^atms/Agtpbp1^atms MRL/Mp-Agtpbp1^atms Fas^lpr	decreased spleen weight	J:103944
Agtpbp1^babe/Agtpbp1^babe C57BL/6JSfdAnu-Agtpbp1^babe/Anu	ataxia	J:104190
Agtpbp1^babe/Agtpbp1^babe C57BL/6JSfdAnu-Agtpbp1^babe/Anu	paraparesis	J:104190
Agtpbp1^m2Btlr/Agtpbp1^m2Btlr C57BL/6J-Agtpbp1^m2Btlr	decreased activated sperm motility	J:159361
	decreased body size	J:159361
	tremors	J:159361
Agtpbp1^m3Btlr/Agtpbp1^m3Btlr C57BL/6J-Agtpbp1^m3Btlr	decreased body weight	J:265119
Agtpbp1^m3Btlr/Agtpbp1^m3Btlr C57BL/6J-Agtpbp1^m3Btlr	impaired coordination	J:265119
Agtpbp1^pcd-2J/Agtpbp1^pcd-2J involves: SM/J	abnormal motor coordination/balance	J:74929
	ataxia	J:74929
	normal nervous system phenotype	J:74929
	reduced male fertility	J:74929
Agtpbp1^pcd-3J/Agtpbp1^pcd-3J BALB/cByJ-Agtpbp1^pcd-3J/J	normal behavior/neurological phenotype	J:233744
	normal hematopoietic system phenotype	J:233744
	normal homeostasis/metabolism phenotype	J:233744
Agtpbp1^pcd-3J/Agtpbp1^pcd-3J involves: BALB/cByJ	abnormal cerebellar granule layer morphology	J:74929
	abnormal male germ cell morphology	J:74929
	abnormal mitral cell morphology	J:74929
	abnormal thalamus morphology	J:74929
	asthenozoospermia	J:74929
	ataxia	J:74929
	normal immune system phenotype	J:231311
	male infertility	J:74929
	oligozoospermia	J:74929
	Purkinje cell degeneration	J:74929
	retina photoreceptor degeneration	J:74929
Agtpbp1^pcd-4J/Agtpbp1^pcd-4J involves: C3H * C57BL/6J	ataxia	J:78314
Agtpbp1^pcd-4J/Agtpbp1^pcd-4J involves: C3H * C57BL/6J	Purkinje cell degeneration	J:78314
Agtpbp1^pcd-5J/Agtpbp1^pcd-5J involves: DBA/2J	abnormal photoreceptor inner segment morphology	J:105316
	abnormal photoreceptor outer segment morphology	J:105316
	abnormal retina photoreceptor layer morphology	J:105316
	ataxia	J:83266, J:105316
	male infertility	J:105316
	Purkinje cell degeneration	J:83266, J:105316
	retina degeneration	J:105316
	small cerebellum	J:105316
	thin retina outer nuclear layer	J:105316
Agtpbp1^pcd-6J/Agtpbp1⁺ C57BL/6J-Agtpbp1^pcd-6J/J	reduced fertility	J:87349
Agtpbp1^pcd-6J/Agtpbp1^pcd-6J C57BL/6J-Agtpbp1^pcd-6J/J	abnormal olfactory bulb morphology	J:87349
	abnormal ventral spinal root morphology	J:87349
	ataxia	J:87349
	azoospermia	J:87349
	decreased skeletal muscle fiber size	J:87349
	infertility	J:87349
	Purkinje cell degeneration	J:87349
	retina degeneration	J:87349
	testicular atrophy	J:87349
Agtpbp1^pcd-7J/Agtpbp1^pcd-7J C.Cg-Ighm^tm1Cgn Agtpbp1^pcd-7J	abnormal auditory brainstem response	J:96855
	ataxia	J:96855
	enlarged hippocampus	J:96855
	Purkinje cell degeneration	J:96855
Agtpbp1^pcd-8J/Agtpbp1^pcd-8J BALB/cJ-Agtpbp1^pcd-8J/GrsrJ	abnormal male germ cell morphology	J:132487
	abnormal retina layer morphology	J:132487
	ataxia	J:132487
	decreased body size	J:132487
	decreased Purkinje cell number	J:132487
	male infertility	J:132487
	reduced female fertility	J:132487
	retina degeneration	J:132487
Agtpbp1^pcd-Btlr/Agtpbp1^pcd-Btlr C57BL/6J-Agtpbp1^pcd-Btlr	ataxia	J:133627
	male infertility	J:133627
	normal nervous system phenotype	J:133627
	oligozoospermia	J:133627
	Purkinje cell degeneration	J:133627
	retina photoreceptor degeneration	J:133627
	teratozoospermia	J:133627
Agtpbp1^{pcd-Tg(Dhfr)1Jwg}/Agtpbp1^{pcd-Tg(Dhfr)1Jwg} involves: C57BL/6J * CD-1 * DBA/2J	abnormal olfactory bulb morphology	J:9814, J:14991
	ataxia	J:9814, J:14991
	azoospermia	J:9814
	decreased litter size	J:9814
	male infertility	J:9814, J:14991
	Purkinje cell degeneration	J:9814, J:14991
	retina photoreceptor degeneration	J:9814, J:14991
Agtpbp1^pcd/Agtpbp1^pcd B6.BR-Agtpbp1^pcd/J	abnormal photoreceptor connecting cilium morphology	J:249732
Agtpbp1^pcd/Agtpbp1^pcd B6.BR-Agtpbp1^pcd/J	retina photoreceptor degeneration	J:249732
Agtpbp1^pcd/Agtpbp1^pcd involves: C57BL/6J * C57BR/cdJ * DBA/2J	abnormal cone electrophysiology	J:189268
	abnormal eye electrophysiology	J:189268
	abnormal retina inner plexiform layer morphology	J:189268
	abnormal retina outer nuclear layer morphology	J:189268
	abnormal retina rod cell morphology	J:189268
	abnormal rod electrophysiology	J:189268
	decreased amacrine cell number	J:189268
	retina photoreceptor degeneration	J:189268
	thin retina outer nuclear layer	J:189268
Agtpbp1^pcd/Agtpbp1^pcd involves: C57BR/cdJ	abnormal cochlear VIII nucleus morphology	J:121314
Agtpbp1^pcd/Agtpbp1^pcd involves: C57BR/cdJ	decreased Purkinje cell number	J:121314
Agtpbp1^pcd/Agtpbp1^pcd involves: C57BR/cdJ * CBA	abnormal cerebellar granule layer morphology	J:5613
	abnormal cerebellar Purkinje cell layer	J:23733, J:106414
	abnormal male germ cell morphology	J:5613
	abnormal olfactory bulb morphology	J:5613
	abnormal Purkinje cell dendrite morphology	J:23733
	abnormal thalamus morphology	J:5613
	asthenozoospermia	J:5613
	ataxia	J:5613
	decreased Purkinje cell number	J:106414
	male infertility	J:5613
	oligozoospermia	J:5613
	Purkinje cell degeneration	J:5613
	reduced female fertility	J:5613
	retina photoreceptor degeneration	J:5613

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