Havcr1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Havcr1
hepatitis A virus cellular receptor 1
MGI:2159680

20 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Havcr1^tm1Kuch/Havcr1^tm1Kuch B6.Cg-Havcr1^tm1Kuch	abnormal B cell physiology	J:186484
	abnormal CD4-positive, alpha-beta T cell physiology	J:186484
	abnormal dendritic cell physiology	J:186484
	abnormal T cell differentiation	J:186484
	autoimmune response	J:186484
	enlarged spleen	J:186484
	increased activated T cell number	J:186484
	increased anti-double stranded DNA antibody level	J:186484
	increased CD4-positive, alpha-beta T cell number	J:186484
	increased CD8-positive, alpha-beta T cell number	J:186484
	increased double-negative T cell number	J:186484
	increased T cell number	J:186484
Havcr1^tm1Shw/Havcr1^tm1Shw C.129P2-Havcr1^tm1Shw	normal immune system phenotype	J:166400
Havcr1^tm1Vlcg/Havcr1^tm1Vlcg B6.129-Havcr1^tm1Vlcg	normal immune system phenotype	J:187793
	increased interleukin-5 secretion	J:187793
	increased interleukin-13 secretion	J:187793
Havcr1^tm1Vlcg/Havcr1^tm1Vlcg C.129-Havcr1^tm1Vlcg	abnormal cytokine secretion	J:187793
	normal immune system phenotype	J:187793
	increased interleukin-4 secretion	J:187793
	increased interleukin-5 secretion	J:187793
	increased interleukin-10 secretion	J:187793
	increased interleukin-13 secretion	J:187793
	increased interleukin-17 secretion	J:187793
	respiratory system inflammation	J:187793

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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