Bmf Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bmf
BCL2 modifying factor
MGI:2176433

23 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bmf^tm1.1Ast/Bmf^tm1.1Ast B6.Cg-Bmf^tm1.1Anst	abnormal B cell morphology	J:133084
	abnormal immune system cell morphology	J:133084
	abnormal spleen morphology	J:133084
	decreased B cell apoptosis	J:133084
	decreased T cell apoptosis	J:133084
	enlarged spleen	J:133084
	increased follicular B cell number	J:133084
	increased immature B cell number	J:133084
	increased immunoglobulin level	J:133084
	increased mature B cell number	J:133084
	increased pre-B cell number	J:133084
	increased T cell derived lymphoma incidence	J:133084
	increased transitional stage B cell number	J:133084
	normal neoplasm	J:133084
	spleen hyperplasia	J:133084
Bmf^tm1.1Ast/Bmf^tm1.1Ast involves: C57BL/6	abnormal involution of the mammary gland	J:235354
Bmf^tm1Rjd/Bmf^tm1Rjd B6.129S6-Bmf^tm1Rjd	decreased T cell apoptosis	J:153652
	enlarged spleen	J:153652
	hydrometrocolpos	J:153652
	increased B cell number	J:153652
	increased CD8-positive, alpha-beta T cell number	J:153652
	increased splenocyte number	J:153652
	vagina atresia	J:153652
Bmf^tm2.1Rjd/Bmf^tm2.1Rjd B6.129S6-Bmf^tm2.1Rjd	no abnormal phenotype detected	J:153652
Bmf^tm3.1Rjd/Bmf^tm3.1Rjd B6.129S6-Bmf^tm3.1Rjd	decreased CD4-positive, alpha-beta T cell number	J:153652

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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